Network Biology Lab - User contributions [en]

People:JH Shin

2015-03-09T06:00:04Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Genetic architecture interpretation
*Genomics and Epigenetics

==Publications==
* Hanhae Kim, Kwang-Woo Jung, Shinae Maeng, Ying-Lien Chen, '''Junha Shin''', Jung Eun Shim, Sohyun Hwang, Guilhem Janbon, Taeyup Kim, Joseph Heitman, Yong-Sun Bahn and Insuk Lee, Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans. ''Sci Rep. 5: 8767. (2015)'', doi: 10.1038/srep08767
* Hanhae Kim, Jung Eun Shim, '''Junha Shin''' and Insuk Lee, EcoliNet: a database of cofunctional gene network for Escherichia coli. ''Database 2015: bav001. (2015)'', doi: 10.1093/database/bav001
* Tak Lee, Sunmo Yang, Eiru Kim, Younhee Ko, Sohyun Hwang, '''Junha Shin''', Jung Eun Shim, Hongseok Shim, Hyojin Kim, Chanyoung Kim and Insuk Lee, AraNet v2: an improved database of co-functional gene networks for the study of Arabidopsis thaliana and 27 other nonmodel plant species, ''Nucleic Acids Research, 43 (D1): D996-D1002 (2015)''
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, ''Nucleic Acids Research, 42 (Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology, 15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications, 412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research, 20 (8), 1143-1153 (2010)''

People:JH Shin

2015-03-09T05:58:14Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Genetic architecture interpretation
*Genomics and Epigenetics

==Publications==
* Hanhae Kim, Kwang-Woo Jung, Shinae Maeng, Ying-Lien Chen, '''Junha Shin''', Jung Eun Shim, Sohyun Hwang, Guilhem Janbon, Taeyup Kim, Joseph Heitman, Yong-Sun Bahn and Insuk Lee, Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans. ''Sci Rep. 5:8767. (2015)'', doi: 10.1038/srep08767
* Hanhae Kim, Jung Eun Shim, '''Junha Shin''' and Insuk Lee, EcoliNet: a database of cofunctional gene network for Escherichia coli. ''Database 2015 : bav001. (2015)'', doi: 10.1093/database/bav001
* Tak Lee, Sunmo Yang, Eiru Kim, Younhee Ko, Sohyun Hwang, '''Junha Shin''', Jung Eun Shim, Hongseok Shim, Hyojin Kim, Chanyoung Kim and Insuk Lee, AraNet v2: an improved database of co-functional gene networks for the study of Arabidopsis thaliana and 27 other nonmodel plant species, ''Nucleic Acids Research, 43 (D1): D996-D1002 (2015)''
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, ''Nucleic Acids Research, 42 (Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology, 15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications, 412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research, 20 (8), 1143-1153 (2010)''

People:JH Shin

2015-03-09T05:54:12Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Genetic architecture interpretation
*Genomics and Epigenetics

==Publications==
* Hanhae Kim, Jung Eun Shim, '''Junha Shin''' and Insuk Lee, EcoliNet: a database of cofunctional gene network for Escherichia coli. ''Database (2015) 2015 : bav001.'', doi: 10.1093/database/bav001
* Tak Lee, Sunmo Yang, Eiru Kim, Younhee Ko, Sohyun Hwang, '''Junha Shin''', Jung Eun Shim, Hongseok Shim, Hyojin Kim, Chanyoung Kim and Insuk Lee, AraNet v2: an improved database of co-functional gene networks for the study of Arabidopsis thaliana and 27 other nonmodel plant species, ''Nucleic Acids Research, 43 (D1): D996-D1002 (2015)''
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, ''Nucleic Acids Research, 42 (Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology, 15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications, 412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research, 20 (8), 1143-1153 (2010)''

People:JH Shin

2015-01-16T02:56:18Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Genetic architecture interpretation
*Genomics and Epigenetics

==Publications==
* Tak Lee, Sunmo Yang, Eiru Kim, Younhee Ko, Sohyun Hwang, '''Junha Shin''', Jung Eun Shim, Hongseok Shim, Hyojin Kim, Chanyoung Kim and Insuk Lee, AraNet v2: an improved database of co-functional gene networks for the study of Arabidopsis thaliana and 27 other nonmodel plant species, ''Nucleic Acids Research, 43 (D1): D996-D1002 (2015)''
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, ''Nucleic Acids Research, 42 (Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology, 15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications, 412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research, 20 (8), 1143-1153 (2010)''

People:JH Shin

2015-01-16T02:55:53Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Genetic architecture interpretation
*Genomics and Epigenetics

==Publications==
* Tak Lee, Sunmo Yang, Eiru Kim, Younhee Ko, Sohyun Hwang, '''Junha Shin''', Jung Eun Shim, Hongseok Shim, Hyojin Kim, Chanyoung Kim and Insuk Lee, AraNet v2: an improved database of co-functional gene networks for the study of Arabidopsis thaliana and 27 other nonmodel plant species, ''Nucleic Acids Research, 43 (D1): D996-D1002''
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, ''Nucleic Acids Research, 42 (Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology, 15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications, 412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research, 20 (8), 1143-1153 (2010)''

People:JH Shin

2014-07-14T11:47:09Z

Espjun: /* Current Research Interests */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Genetic architecture interpretation
*Genomics and Epigenetics

==Publications==
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, ''Nucleic Acids Research, 42 (Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology, 15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications, 412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research, 20 (8), 1143-1153 (2010)''

People:JH Shin

2014-07-14T07:19:58Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, ''Nucleic Acids Research, 42 (Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology, 15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications, 412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research, 20 (8), 1143-1153 (2010)''

People:JH Shin

2014-07-14T07:18:19Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, ''Nucleic Acids Res, 42 (Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology, 15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications, 412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research, 20 (8), 1143-1153 (2010)''

People:JH Shin

2014-07-14T07:17:00Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* Ara Cho, '''Junha Shin''', Sohyun Hwang, Chanyung Kim, Hongsuk Shim, Hyojin Kim, Hanhae Kim, Insuk Lee, WormNet v3: a network-assisted hypothesis-generating server for Caenorhabditis elegans, '''''Nucleic Acids Res''''', ''42(Web Server issue), W76 - 82 (2014)''
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', ''10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, '''''Nucleic Acids Research''''', ''42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. '''''Biochemical and Biophysical Research Communications''''', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. '''''Genome Research''''', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-27T15:28:58Z

Espjun: /* Junha Shin */

People:JH Shin

2014-05-27T15:21:09Z

Espjun: /* Junha Shin */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
:: '''Thesis''': Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
:: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', ''10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, '''''Nucleic Acids Research''''', ''42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. '''''Biochemical and Biophysical Research Communications''''', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. '''''Genome Research''''', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-27T15:19:30Z

Espjun: /* Junha Shin */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
:: '''Thesis''' : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
:: ''Theme'' : ''Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', ''10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, '''''Nucleic Acids Research''''', ''42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. '''''Biochemical and Biophysical Research Communications''''', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. '''''Genome Research''''', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-27T15:18:11Z

Espjun: /* Junha Shin */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
:: '''Thesis''' : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
:: ''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', ''10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, '''''Nucleic Acids Research''''', ''42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. '''''Biochemical and Biophysical Research Communications''''', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. '''''Genome Research''''', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-27T15:15:47Z

Espjun: /* Junha Shin */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', Dept. of Biotechnology, Yonsei University (09/2008 – 02/2014)
'''Thesis''' : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S & Ph.D program, Dept. of Biology, Yonsei University (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', Dept. of Biology, Yonsei University (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', ''10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, '''''Nucleic Acids Research''''', ''42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. '''''Biochemical and Biophysical Research Communications''''', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. '''''Genome Research''''', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-27T15:12:08Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Thesis : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S and Ph.D program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', ''10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, '''''Nucleic Acids Research''''', ''42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. '''''Biochemical and Biophysical Research Communications''''', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. '''''Genome Research''''', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-27T15:09:24Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Thesis : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S and Ph.D program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''Mol. BioSyst.''', ''10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-27T15:05:52Z

Espjun: /* Current Research Interests */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Thesis : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S and Ph.D program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems Biology and Network Biology
*Comparative Genomics
*Epigenomics

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-26T03:15:26Z

Espjun:

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Thesis : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S and Ph.D program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Gene network construction and analysis for various model organisms.
*Comparative Genomics
*Epigenomics

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-26T03:12:05Z

Espjun:

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Thesis : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S and Ph.D program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Comparative Genomics
*Epigenomics
*Gene network construction and analysis for various model organisms.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-26T03:11:25Z

Espjun:

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Thesis : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S and Ph.D program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Comparative Genomics
*Epigenomics
*Gene network construction and analysis for various model organisms.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-26T03:09:03Z

Espjun: /* Junha Shin */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Thesis : Improved methods of functional gene network construction by reinforced genomic context information
*Combined M.S and Ph.D program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-26T03:08:24Z

Espjun: /* Junha Shin */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Thesis : Improved methods of functional gene network construction by reinforced genomic context information
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
''Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells''
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-26T03:05:19Z

Espjun: /* Junha Shin */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D''', ''Yonsei university'', Dept. of Biotechnology (09/2008 – 02/2014)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2014-05-26T03:03:42Z

Espjun: /* Junha Shin */

People:JH Shin

2014-01-23T01:32:18Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research, 42 (D1), D731-D736 (2014)''
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2013-12-03T10:42:02Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research'',
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''

People:JH Shin

2013-11-29T04:47:35Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research'',
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), 1143-1153 (2010)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), 454-459 (2011)''

People:JH Shin

2013-11-29T04:47:05Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research'',
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20 (8), pp1143-1153 (2010)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412 (3), pp454-459 (2011)''

People:JH Shin

2013-11-29T04:46:02Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29 (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research'',
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20(8), pp1143-1153 (2010)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412(3), pp454-459 (2011)''

People:JH Shin

2013-11-29T04:45:31Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst., 10 (1), 24 - 29., (2014)''
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research'',
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20(8), pp1143-1153 (2010)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412(3), pp454-459 (2011)''

People:JH Shin

2013-11-29T04:44:50Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* '''Junha Shin''', Tak Lee, Hanhae Kim and Insuk Lee, Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. ''Mol. BioSyst.'', 10 (1), 24 - 29., (2014)
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research'',
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20(8), pp1143-1153 (2010)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412(3), pp454-459 (2011)''

Publications

2013-11-29T04:43:17Z

Espjun:

*[http://scholar.google.com/citations?user=3uHQIOkAAAAJ Google Scholar citation report]
{{#widget:AddHtml
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}}

* '*' co-corresponding authorship
==2014==
*33. Junha Shin, Tak Lee, Hanhae Kim and '''Insuk Lee''', Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', 10 (1), 24 - 29., (2014) [http://www.ncbi.nlm.nih.gov/pubmed/24194096 Pubmed][http://pubs.rsc.org/en/content/articlepdf/2014/mb/c3mb70366e pdf]

==2013==
*32. Eiru Kim, Hanhae Kim and '''Insuk Lee''', JiffyNet: a web-based instant protein network modeler for newly sequenced species. '''''Nucleic Acids Research''''' 41 (W1): W192-W197., (2013) [http://www.ncbi.nlm.nih.gov/pubmed/23685435 Pubmed][http://nar.oxfordjournals.org/content/early/2013/05/17/nar.gkt419.full.pdf+html pdf]
*31. '''Insuk Lee''', Network approaches to the genetic dissection of phenotypes in animals and humans. '''''Animal Cells and Systems''''' Vol.17,No.2,75-79(2013)[http://www.tandfonline.com/doi/abs/10.1080/19768354.2013.789076 Link]

==2012==
*30. Peggy I Wang, Sohyun Hwang, Rodney P Kincaid, Christopher S Sullivan, '''Insuk Lee*''', and Edward M Marcotte*. RIDDLE: Reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network. '''''Genome Biology''''' 13:R125 (2012)[http://www.ncbi.nlm.nih.gov/pubmed/23268829 pubmed]
*29. Lee Chae*, '''Insuk Lee*''', Junha Shin, and Seung Yon Rhee*. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''' 15:177-184 (2012)[http://www.ncbi.nlm.nih.gov/pubmed/22280840 pubmed] [[media:CurrOpinPlantBiol 15-177.pdf|pdf]]
*28. Stephanie M. Quanbeck, Libuse Brachova, Alexis A. Campbell, Xin Guan, Ann Perera, Kun He, Seung Y. Rhee, Preeti Bais, Julie A. Dickerson, Philip Dixon, Gert Wohlgemuth, Oliver Fiehn, Lenore Barken, Iris Lange, B. Markus Lange, '''Insuk Lee''', Diego Cortes, Carolina Salazar, Joel Shuman, Vladimir Shulaev, David V. Huhman, Lloyd W. Sumner, Mary R. Roth, Ruth Welti, Hilal Ilarslan, Eve S. Wurtele, and Basil J. Nikolau. Metabolomics as a hypothesis-generating functional genomics tool for the annotation of Arabidopsis thaliana genes of “unknown function”. '''''Frontiers in Plant Science''''' 3:1-12 (2012) [http://www.ncbi.nlm.nih.gov/pubmed/22645570/ pubmed][[media:Fpls-03-00015.pdf|pdf]]

==2011==
*27. '''Insuk Lee*''', Young-Su Seo, Dusica Coltrane, Sohyun Hwang, Taeyun Oh, Edward M. Marcotte*, and Pamela C. Ronald*. Genetic dissection of the biotic stress response using a genome-scale gene network for rice. '''''PNAS''''' 108(45):18548-53 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/22042862 pubmed] [[media:PNAS-2011-Lee-18548-53.pdf|pdf]]

*26. Sohyun Hwang, Seung Y. Rhee*, Edward M. Marcotte*, and '''Insuk Lee*'''. Systematic prediction of candidate gene function associated to phenotype traits using the probabilistic functional gene network of Arabidopsis thaliana. '''''Nature Protocols''''' 6:1429-1442 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21886106 pubmed][[media:2011.08.25.online.nprot.2011.372.pdf|pdf]]

*25. '''Insuk Lee''', Probabilistic functional gene societies. '''''Progress in Biophysics and Molecular Biology''''' 106:435-442 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21281658 pubmed] [[media:Publications_023_n.pdf|pdf]]

*24. '''Insuk Lee*''', U. Martin Blom, Peggy I. Wang, Jung Eun Shim, and Edward M. Marcotte*. Prioritizing candidate disease genes by network-based boosting of genome-wide association data. '''''Genome Research''''' 21:1109-1121 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21536720 pubmed] [[media:Publications_025_n.pdf|pdf]]

*23. Young-Su Seo, Mawsheng Chern, Laura E. Bartley, Muho Han, Ki-Hong Jung, '''Insuk Lee''', Harkamal Walia, Todd Richter, Xia Xu, Peijian Cao, Wei Bai, Rajeshwari Ramanan, Fawn Amonpant, Loganathan Arul, Patrick E. Canlas, Randy Ruan, Chang-Jin Park, Xuewel Chen, Sohyun Hwang, Jong-Seong Jeon, and Pamela C. Ronald. Towards establishment of a rice stress response interactome. '''''PLoS Genetics''''' 7(4):e1002020 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21533176 pubmed] [[media:Publications_024.pdf|pdf]]

==2010==
*22. Ni Huang, '''Insuk Lee''', Edward M.Marcotte, Matthew E.Hurles, Characterising and predicting haploinsufficiency in the human genome, '''''PLoS Genet.''''' 6(10):e1001154(2010) [http://www.ncbi.nlm.nih.gov/pubmed/20976243 pubmed] [[media:Publications_022.pdf|pdf]]

*21. Eiru Kim, Jaeyoon Shin and '''Insuk Lee''', Assessment of effectiveness of the network-guided genetic screen, '''''Mol Biosyst.''''' 6:1803-1806(2010) [http://www.ncbi.nlm.nih.gov/pubmed/20697632 pubmed] [[media:Publications_021.pdf|pdf]]

*20. '''Insuk Lee*''', Ben Lehner, Tanya Vavouri, Junha Shin, Andrew G. Fraser, and Edward M. Marcotte, Predicting genetic modifier loci using functional gene networks, '''''Genome Research''''', 20:1143-1153(2010) . co-corresponding author [http://www.ncbi.nlm.nih.gov/pubmed/20538624 pubmed] [[media:Publications_020.pdf|pdf]]

*19. '''Insuk Lee*''', Bindu Ambaru, Pranjali Thakkar, Edward M Marcotte*, Seung Y Rhee*, Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana, '''''Nature Biotechnology''''', 28:149-156 (2010). ''co-corresponding author'' [http://www.ncbi.nlm.nih.gov/pubmed/20118918 pubmed] [[media:Publications_019.pdf|pdf]]
==2009==
*18. '''Insuk Lee''' and Edward Marcotte. Effects of functional bias on supervised learning of a gene network model. '''In Methods in Molecular Biology''' Vol. 541, Computational Systems Biology (ed. R. Ireton, K. Montgomery, J. McDermott, R. Samudrala, R. Bumgarner). Totowa, THE HUMANA. p463-475 (2009) [http://www.ncbi.nlm.nih.gov/pubmed/19381535 pubmed] [[media:Publications_018.pdf|pdf]]

*17. Zhihua Li, '''Insuk Lee''', Emily Moradi, Nai-Jung Hung, Arlen W. Johnson, Edward M. Marcotte, Rational Extension of the Ribosome Biogenesis Pathway Using Network-Guided Genetics, '''''PLoS Biology''''', 7(10):e1000213 (2009) [http://www.ncbi.nlm.nih.gov/pubmed/19806183 pubmed] [[media:Publications_017.pdf|pdf]]

*16. Ryan S. Gray, Philip B. Abitua, Bogdan J. Wlodarczyk, Heather L. Szabo-Rogers, Otis Blanchard, '''Insuk Lee''', Greg S. Weiss, Karen J. Liu, Edward M. Marcotte, John B. Wallingford, Richard H. Finnell. The planar cell polarity effector protein Fuz is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development, '''''Nature Cell Biology''''' 11:1225-32 (2009) '''''*Cover story''''' [http://www.ncbi.nlm.nih.gov/pubmed/19767740 pubmed] [[media:Publications_016.pdf|pdf]]
==2008==
*15. Ben Lehner* and '''Insuk Lee*'''. Network-guided genetic screening: building, testing, and using gene networks to predict gene function. '''''Brief. Funct. Genomic'''''. 7:217-227 (2008). '''''co-corresponding author''''' [http://www.ncbi.nlm.nih.gov/pubmed/18445637 pubmed] [[media:Publications_015.pdf|pdf]]

*14. '''Insuk Lee''' and Edward Marcotte. Integrating Functional Genomics Data. '''In Methods in Molecular Biology''' Vol. 453, Bioinformatics Vol. II (ed. Jonathan Keith). Totowa, THE HUMANA. p267-278 (2008) [http://www.ncbi.nlm.nih.gov/pubmed/18712309 pubmed] [[media:Publications_014.pdf|pdf]]

*13. '''Insuk Lee''', Ben Lehner, Catriona Crombie, Wendy Wong, Andrew G. Fraser, Edward M. Marcotte. A single gene network accurately predicts phenotypic effects of gene perturbation in ''Caenorhabditis elegans''. '''''Nature Genetics''''' 40:181-188 (2008). '''''*Cover story''''' [http://www.ncbi.nlm.nih.gov/pubmed/18223650 pubmed] [[media:Publications_013.pdf|pdf]] This paper was the subject of the following commentary (Natalie de Souza, Networking on organism. Nature Methods 5:217), and minireviews (Von Stetina S. E. and Mango S. E. Wormnet: a crystal ball for Caenorhabditis elegans. Genome Biology 9:226. Borgwardt K. Predicting phenotypic effects of gene perturbations in C. elegans using an integrated network model. BioEssays 30:707)

==Before 2007==
*12. '''Insuk Lee''', Rammohan Narayanaswamy, Edward Marcotte. Bioinformatic prediction of yeast gene function. '''In METHOD IN MICROBIOLOGY''' Vol. 36, Yeast Gene Analysis (ed. Ian Stansfield and Mike Stark), Elsevier. p597-628, (2007) [[media:Publications_012.pdf|pdf]]

*11. Kris McGary, '''Insuk Lee''', Edward M. Marcotte. Broad network-based predictability of S. cerevisiae gene loss-of-function phenotypes. '''''Genome Biology''''' 8:R258 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/18053250 pubmed] [[media:Publications_011.pdf|pdf]]

*10. '''Insuk Lee''', Zhihua Li, and Edward M. Marcotte. An improved bias-reduced probabilistic functional gene network of baker’s yeast ''Saccharomyces cerevisiae''. '''''PLOS One''''' 2:e988 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/17912365 pubmed] [[media:Publications_010.pdf|pdf]]

*9. Hart G. Traver, '''Insuk Lee''', Edward Marcotte. A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality. '''''BMC Bioinformatic''''' 8:236 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/17605818 pubmed] [[media:Publications_009.pdf|pdf]]

*8. Insuk Lee, Shailesh V. Date, Alex T. Adai, Edward Marcotte. A Probabilistic functional network of yeast genes. '''''Science''''' 306:1555-1558, (2004) [http://www.ncbi.nlm.nih.gov/pubmed/15567862 pubmed] [[media:Publications_008.pdf|pdf]]

*7. Bork, P., Jensen, L.J., Von Mering, C., Ramani, A.K., '''Lee I''', Marcotte, E.M. Protein interaction networks from yeast to human. '''''Curr. Opin. Struct. Biol.''''' 14:292-9, (2004) [http://www.ncbi.nlm.nih.gov/pubmed/15193308 pubmed] [[media:Publications_007.pdf|pdf]]

*6. '''Insuk Lee''' and Rasika Harshey. Patterns of Sequence conservation at termini of LTR retrotransposons and DNA transposons in the human genome: Lessons from phage Mu. '''''Nucleic Acids Res.''''' 31:4531-4540, (2003)

*5. '''Insuk Lee''' and Rasika Harshey. The conserved CA/TG motif at Mu termini: T specifies stable transpososome assembly. '''''J. Mol. Biol.''''' 330:261-275, (2003)

*4. '''Insuk Lee''' and Rasika Harshey. Importance of the conserved CA dinucleotide at Mu termini. '''''J. Mol. Biol.''''' 314:433-444, (2001)

*3. Xue, Y., Bai, X., '''Lee, I.''', Kallstrom, G., Ho, J., Brown, J., Stevens, A., and Johnson, A. W. Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. '''''Mol. Cell. Biol.''''' 20:4006-4015, (2000)

*2. Liu, J., Gong, Y., Prakash, O., Wen, L., '''Lee, I'''., Huang J.,-K., and Krishnamoorthi, R. NMR studies of internal dynamics of serine proteinase protein inhibitors: Binding region mobilities of intact and reactive-site hydrolyzed CMTI-III of the squash family and comparison with those of counterparts of CMTI-V of the potato I family. '''''Protein Science''''' 7:132-141, (1998)

*1. Wen, L., '''Lee, I.''', Chen, G., Huang, J.,-K., Gong, Y., and Krishnamoorthi, R. Changing the inhibitory specificity and function of CMTI-V by site-directed mutagenesis. '''''Biochem. Biophys. Res. Commun.''''' 207:897-902, (1995)

Publications

2013-11-29T04:43:05Z

Espjun:

*[http://scholar.google.com/citations?user=3uHQIOkAAAAJ Google Scholar citation report]
{{#widget:AddHtml
|content=<a title="Insuk Lee's Profile" href='http://www.researcherid.com/rid/F-7722-2010' target='_blank'><img src='http://labs.researcherid.com/mashlets/badge/rid-idsymbol4.gif' border='0'></a>
}}

* '*' co-corresponding authorship
==2013==
*33. Junha Shin, Tak Lee, Hanhae Kim and '''Insuk Lee''', Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', 10 (1), 24 - 29., (2014) [http://www.ncbi.nlm.nih.gov/pubmed/24194096 Pubmed][http://pubs.rsc.org/en/content/articlepdf/2014/mb/c3mb70366e pdf]

==2013==
*32. Eiru Kim, Hanhae Kim and '''Insuk Lee''', JiffyNet: a web-based instant protein network modeler for newly sequenced species. '''''Nucleic Acids Research''''' 41 (W1): W192-W197., (2013) [http://www.ncbi.nlm.nih.gov/pubmed/23685435 Pubmed][http://nar.oxfordjournals.org/content/early/2013/05/17/nar.gkt419.full.pdf+html pdf]
*31. '''Insuk Lee''', Network approaches to the genetic dissection of phenotypes in animals and humans. '''''Animal Cells and Systems''''' Vol.17,No.2,75-79(2013)[http://www.tandfonline.com/doi/abs/10.1080/19768354.2013.789076 Link]

==2012==
*30. Peggy I Wang, Sohyun Hwang, Rodney P Kincaid, Christopher S Sullivan, '''Insuk Lee*''', and Edward M Marcotte*. RIDDLE: Reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network. '''''Genome Biology''''' 13:R125 (2012)[http://www.ncbi.nlm.nih.gov/pubmed/23268829 pubmed]
*29. Lee Chae*, '''Insuk Lee*''', Junha Shin, and Seung Yon Rhee*. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''' 15:177-184 (2012)[http://www.ncbi.nlm.nih.gov/pubmed/22280840 pubmed] [[media:CurrOpinPlantBiol 15-177.pdf|pdf]]
*28. Stephanie M. Quanbeck, Libuse Brachova, Alexis A. Campbell, Xin Guan, Ann Perera, Kun He, Seung Y. Rhee, Preeti Bais, Julie A. Dickerson, Philip Dixon, Gert Wohlgemuth, Oliver Fiehn, Lenore Barken, Iris Lange, B. Markus Lange, '''Insuk Lee''', Diego Cortes, Carolina Salazar, Joel Shuman, Vladimir Shulaev, David V. Huhman, Lloyd W. Sumner, Mary R. Roth, Ruth Welti, Hilal Ilarslan, Eve S. Wurtele, and Basil J. Nikolau. Metabolomics as a hypothesis-generating functional genomics tool for the annotation of Arabidopsis thaliana genes of “unknown function”. '''''Frontiers in Plant Science''''' 3:1-12 (2012) [http://www.ncbi.nlm.nih.gov/pubmed/22645570/ pubmed][[media:Fpls-03-00015.pdf|pdf]]

==2011==
*27. '''Insuk Lee*''', Young-Su Seo, Dusica Coltrane, Sohyun Hwang, Taeyun Oh, Edward M. Marcotte*, and Pamela C. Ronald*. Genetic dissection of the biotic stress response using a genome-scale gene network for rice. '''''PNAS''''' 108(45):18548-53 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/22042862 pubmed] [[media:PNAS-2011-Lee-18548-53.pdf|pdf]]

*26. Sohyun Hwang, Seung Y. Rhee*, Edward M. Marcotte*, and '''Insuk Lee*'''. Systematic prediction of candidate gene function associated to phenotype traits using the probabilistic functional gene network of Arabidopsis thaliana. '''''Nature Protocols''''' 6:1429-1442 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21886106 pubmed][[media:2011.08.25.online.nprot.2011.372.pdf|pdf]]

*25. '''Insuk Lee''', Probabilistic functional gene societies. '''''Progress in Biophysics and Molecular Biology''''' 106:435-442 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21281658 pubmed] [[media:Publications_023_n.pdf|pdf]]

*24. '''Insuk Lee*''', U. Martin Blom, Peggy I. Wang, Jung Eun Shim, and Edward M. Marcotte*. Prioritizing candidate disease genes by network-based boosting of genome-wide association data. '''''Genome Research''''' 21:1109-1121 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21536720 pubmed] [[media:Publications_025_n.pdf|pdf]]

*23. Young-Su Seo, Mawsheng Chern, Laura E. Bartley, Muho Han, Ki-Hong Jung, '''Insuk Lee''', Harkamal Walia, Todd Richter, Xia Xu, Peijian Cao, Wei Bai, Rajeshwari Ramanan, Fawn Amonpant, Loganathan Arul, Patrick E. Canlas, Randy Ruan, Chang-Jin Park, Xuewel Chen, Sohyun Hwang, Jong-Seong Jeon, and Pamela C. Ronald. Towards establishment of a rice stress response interactome. '''''PLoS Genetics''''' 7(4):e1002020 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21533176 pubmed] [[media:Publications_024.pdf|pdf]]

==2010==
*22. Ni Huang, '''Insuk Lee''', Edward M.Marcotte, Matthew E.Hurles, Characterising and predicting haploinsufficiency in the human genome, '''''PLoS Genet.''''' 6(10):e1001154(2010) [http://www.ncbi.nlm.nih.gov/pubmed/20976243 pubmed] [[media:Publications_022.pdf|pdf]]

*21. Eiru Kim, Jaeyoon Shin and '''Insuk Lee''', Assessment of effectiveness of the network-guided genetic screen, '''''Mol Biosyst.''''' 6:1803-1806(2010) [http://www.ncbi.nlm.nih.gov/pubmed/20697632 pubmed] [[media:Publications_021.pdf|pdf]]

*20. '''Insuk Lee*''', Ben Lehner, Tanya Vavouri, Junha Shin, Andrew G. Fraser, and Edward M. Marcotte, Predicting genetic modifier loci using functional gene networks, '''''Genome Research''''', 20:1143-1153(2010) . co-corresponding author [http://www.ncbi.nlm.nih.gov/pubmed/20538624 pubmed] [[media:Publications_020.pdf|pdf]]

*19. '''Insuk Lee*''', Bindu Ambaru, Pranjali Thakkar, Edward M Marcotte*, Seung Y Rhee*, Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana, '''''Nature Biotechnology''''', 28:149-156 (2010). ''co-corresponding author'' [http://www.ncbi.nlm.nih.gov/pubmed/20118918 pubmed] [[media:Publications_019.pdf|pdf]]
==2009==
*18. '''Insuk Lee''' and Edward Marcotte. Effects of functional bias on supervised learning of a gene network model. '''In Methods in Molecular Biology''' Vol. 541, Computational Systems Biology (ed. R. Ireton, K. Montgomery, J. McDermott, R. Samudrala, R. Bumgarner). Totowa, THE HUMANA. p463-475 (2009) [http://www.ncbi.nlm.nih.gov/pubmed/19381535 pubmed] [[media:Publications_018.pdf|pdf]]

*17. Zhihua Li, '''Insuk Lee''', Emily Moradi, Nai-Jung Hung, Arlen W. Johnson, Edward M. Marcotte, Rational Extension of the Ribosome Biogenesis Pathway Using Network-Guided Genetics, '''''PLoS Biology''''', 7(10):e1000213 (2009) [http://www.ncbi.nlm.nih.gov/pubmed/19806183 pubmed] [[media:Publications_017.pdf|pdf]]

*16. Ryan S. Gray, Philip B. Abitua, Bogdan J. Wlodarczyk, Heather L. Szabo-Rogers, Otis Blanchard, '''Insuk Lee''', Greg S. Weiss, Karen J. Liu, Edward M. Marcotte, John B. Wallingford, Richard H. Finnell. The planar cell polarity effector protein Fuz is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development, '''''Nature Cell Biology''''' 11:1225-32 (2009) '''''*Cover story''''' [http://www.ncbi.nlm.nih.gov/pubmed/19767740 pubmed] [[media:Publications_016.pdf|pdf]]
==2008==
*15. Ben Lehner* and '''Insuk Lee*'''. Network-guided genetic screening: building, testing, and using gene networks to predict gene function. '''''Brief. Funct. Genomic'''''. 7:217-227 (2008). '''''co-corresponding author''''' [http://www.ncbi.nlm.nih.gov/pubmed/18445637 pubmed] [[media:Publications_015.pdf|pdf]]

*14. '''Insuk Lee''' and Edward Marcotte. Integrating Functional Genomics Data. '''In Methods in Molecular Biology''' Vol. 453, Bioinformatics Vol. II (ed. Jonathan Keith). Totowa, THE HUMANA. p267-278 (2008) [http://www.ncbi.nlm.nih.gov/pubmed/18712309 pubmed] [[media:Publications_014.pdf|pdf]]

*13. '''Insuk Lee''', Ben Lehner, Catriona Crombie, Wendy Wong, Andrew G. Fraser, Edward M. Marcotte. A single gene network accurately predicts phenotypic effects of gene perturbation in ''Caenorhabditis elegans''. '''''Nature Genetics''''' 40:181-188 (2008). '''''*Cover story''''' [http://www.ncbi.nlm.nih.gov/pubmed/18223650 pubmed] [[media:Publications_013.pdf|pdf]] This paper was the subject of the following commentary (Natalie de Souza, Networking on organism. Nature Methods 5:217), and minireviews (Von Stetina S. E. and Mango S. E. Wormnet: a crystal ball for Caenorhabditis elegans. Genome Biology 9:226. Borgwardt K. Predicting phenotypic effects of gene perturbations in C. elegans using an integrated network model. BioEssays 30:707)

==Before 2007==
*12. '''Insuk Lee''', Rammohan Narayanaswamy, Edward Marcotte. Bioinformatic prediction of yeast gene function. '''In METHOD IN MICROBIOLOGY''' Vol. 36, Yeast Gene Analysis (ed. Ian Stansfield and Mike Stark), Elsevier. p597-628, (2007) [[media:Publications_012.pdf|pdf]]

*11. Kris McGary, '''Insuk Lee''', Edward M. Marcotte. Broad network-based predictability of S. cerevisiae gene loss-of-function phenotypes. '''''Genome Biology''''' 8:R258 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/18053250 pubmed] [[media:Publications_011.pdf|pdf]]

*10. '''Insuk Lee''', Zhihua Li, and Edward M. Marcotte. An improved bias-reduced probabilistic functional gene network of baker’s yeast ''Saccharomyces cerevisiae''. '''''PLOS One''''' 2:e988 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/17912365 pubmed] [[media:Publications_010.pdf|pdf]]

*9. Hart G. Traver, '''Insuk Lee''', Edward Marcotte. A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality. '''''BMC Bioinformatic''''' 8:236 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/17605818 pubmed] [[media:Publications_009.pdf|pdf]]

*8. Insuk Lee, Shailesh V. Date, Alex T. Adai, Edward Marcotte. A Probabilistic functional network of yeast genes. '''''Science''''' 306:1555-1558, (2004) [http://www.ncbi.nlm.nih.gov/pubmed/15567862 pubmed] [[media:Publications_008.pdf|pdf]]

*7. Bork, P., Jensen, L.J., Von Mering, C., Ramani, A.K., '''Lee I''', Marcotte, E.M. Protein interaction networks from yeast to human. '''''Curr. Opin. Struct. Biol.''''' 14:292-9, (2004) [http://www.ncbi.nlm.nih.gov/pubmed/15193308 pubmed] [[media:Publications_007.pdf|pdf]]

*6. '''Insuk Lee''' and Rasika Harshey. Patterns of Sequence conservation at termini of LTR retrotransposons and DNA transposons in the human genome: Lessons from phage Mu. '''''Nucleic Acids Res.''''' 31:4531-4540, (2003)

*5. '''Insuk Lee''' and Rasika Harshey. The conserved CA/TG motif at Mu termini: T specifies stable transpososome assembly. '''''J. Mol. Biol.''''' 330:261-275, (2003)

*4. '''Insuk Lee''' and Rasika Harshey. Importance of the conserved CA dinucleotide at Mu termini. '''''J. Mol. Biol.''''' 314:433-444, (2001)

*3. Xue, Y., Bai, X., '''Lee, I.''', Kallstrom, G., Ho, J., Brown, J., Stevens, A., and Johnson, A. W. Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. '''''Mol. Cell. Biol.''''' 20:4006-4015, (2000)

*2. Liu, J., Gong, Y., Prakash, O., Wen, L., '''Lee, I'''., Huang J.,-K., and Krishnamoorthi, R. NMR studies of internal dynamics of serine proteinase protein inhibitors: Binding region mobilities of intact and reactive-site hydrolyzed CMTI-III of the squash family and comparison with those of counterparts of CMTI-V of the potato I family. '''''Protein Science''''' 7:132-141, (1998)

*1. Wen, L., '''Lee, I.''', Chen, G., Huang, J.,-K., Gong, Y., and Krishnamoorthi, R. Changing the inhibitory specificity and function of CMTI-V by site-directed mutagenesis. '''''Biochem. Biophys. Res. Commun.''''' 207:897-902, (1995)

Publications

2013-11-29T04:40:53Z

Espjun: /* 2013 */

*[http://scholar.google.com/citations?user=3uHQIOkAAAAJ Google Scholar citation report]
{{#widget:AddHtml
|content=<a title="Insuk Lee's Profile" href='http://www.researcherid.com/rid/F-7722-2010' target='_blank'><img src='http://labs.researcherid.com/mashlets/badge/rid-idsymbol4.gif' border='0'></a>
}}

* '*' co-corresponding authorship
==2013==
*33. Junha Shin, Tak Lee, Hanhae Kim and '''Insuk Lee''', Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction. '''''Mol. BioSyst.''''', 2014, 10 (1), 24 - 29., (2013) [http://www.ncbi.nlm.nih.gov/pubmed/24194096 Pubmed][http://pubs.rsc.org/en/content/articlepdf/2014/mb/c3mb70366e pdf]
*32. Eiru Kim, Hanhae Kim and '''Insuk Lee''', JiffyNet: a web-based instant protein network modeler for newly sequenced species. '''''Nucleic Acids Research''''' 41 (W1): W192-W197., (2013) [http://www.ncbi.nlm.nih.gov/pubmed/23685435 Pubmed][http://nar.oxfordjournals.org/content/early/2013/05/17/nar.gkt419.full.pdf+html pdf]
*31. '''Insuk Lee''', Network approaches to the genetic dissection of phenotypes in animals and humans. '''''Animal Cells and Systems''''' Vol.17,No.2,75-79(2013)[http://www.tandfonline.com/doi/abs/10.1080/19768354.2013.789076 Link]

==2012==
*30. Peggy I Wang, Sohyun Hwang, Rodney P Kincaid, Christopher S Sullivan, '''Insuk Lee*''', and Edward M Marcotte*. RIDDLE: Reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network. '''''Genome Biology''''' 13:R125 (2012)[http://www.ncbi.nlm.nih.gov/pubmed/23268829 pubmed]
*29. Lee Chae*, '''Insuk Lee*''', Junha Shin, and Seung Yon Rhee*. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''' 15:177-184 (2012)[http://www.ncbi.nlm.nih.gov/pubmed/22280840 pubmed] [[media:CurrOpinPlantBiol 15-177.pdf|pdf]]
*28. Stephanie M. Quanbeck, Libuse Brachova, Alexis A. Campbell, Xin Guan, Ann Perera, Kun He, Seung Y. Rhee, Preeti Bais, Julie A. Dickerson, Philip Dixon, Gert Wohlgemuth, Oliver Fiehn, Lenore Barken, Iris Lange, B. Markus Lange, '''Insuk Lee''', Diego Cortes, Carolina Salazar, Joel Shuman, Vladimir Shulaev, David V. Huhman, Lloyd W. Sumner, Mary R. Roth, Ruth Welti, Hilal Ilarslan, Eve S. Wurtele, and Basil J. Nikolau. Metabolomics as a hypothesis-generating functional genomics tool for the annotation of Arabidopsis thaliana genes of “unknown function”. '''''Frontiers in Plant Science''''' 3:1-12 (2012) [http://www.ncbi.nlm.nih.gov/pubmed/22645570/ pubmed][[media:Fpls-03-00015.pdf|pdf]]

==2011==
*27. '''Insuk Lee*''', Young-Su Seo, Dusica Coltrane, Sohyun Hwang, Taeyun Oh, Edward M. Marcotte*, and Pamela C. Ronald*. Genetic dissection of the biotic stress response using a genome-scale gene network for rice. '''''PNAS''''' 108(45):18548-53 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/22042862 pubmed] [[media:PNAS-2011-Lee-18548-53.pdf|pdf]]

*26. Sohyun Hwang, Seung Y. Rhee*, Edward M. Marcotte*, and '''Insuk Lee*'''. Systematic prediction of candidate gene function associated to phenotype traits using the probabilistic functional gene network of Arabidopsis thaliana. '''''Nature Protocols''''' 6:1429-1442 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21886106 pubmed][[media:2011.08.25.online.nprot.2011.372.pdf|pdf]]

*25. '''Insuk Lee''', Probabilistic functional gene societies. '''''Progress in Biophysics and Molecular Biology''''' 106:435-442 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21281658 pubmed] [[media:Publications_023_n.pdf|pdf]]

*24. '''Insuk Lee*''', U. Martin Blom, Peggy I. Wang, Jung Eun Shim, and Edward M. Marcotte*. Prioritizing candidate disease genes by network-based boosting of genome-wide association data. '''''Genome Research''''' 21:1109-1121 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21536720 pubmed] [[media:Publications_025_n.pdf|pdf]]

*23. Young-Su Seo, Mawsheng Chern, Laura E. Bartley, Muho Han, Ki-Hong Jung, '''Insuk Lee''', Harkamal Walia, Todd Richter, Xia Xu, Peijian Cao, Wei Bai, Rajeshwari Ramanan, Fawn Amonpant, Loganathan Arul, Patrick E. Canlas, Randy Ruan, Chang-Jin Park, Xuewel Chen, Sohyun Hwang, Jong-Seong Jeon, and Pamela C. Ronald. Towards establishment of a rice stress response interactome. '''''PLoS Genetics''''' 7(4):e1002020 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21533176 pubmed] [[media:Publications_024.pdf|pdf]]

==2010==
*22. Ni Huang, '''Insuk Lee''', Edward M.Marcotte, Matthew E.Hurles, Characterising and predicting haploinsufficiency in the human genome, '''''PLoS Genet.''''' 6(10):e1001154(2010) [http://www.ncbi.nlm.nih.gov/pubmed/20976243 pubmed] [[media:Publications_022.pdf|pdf]]

*21. Eiru Kim, Jaeyoon Shin and '''Insuk Lee''', Assessment of effectiveness of the network-guided genetic screen, '''''Mol Biosyst.''''' 6:1803-1806(2010) [http://www.ncbi.nlm.nih.gov/pubmed/20697632 pubmed] [[media:Publications_021.pdf|pdf]]

*20. '''Insuk Lee*''', Ben Lehner, Tanya Vavouri, Junha Shin, Andrew G. Fraser, and Edward M. Marcotte, Predicting genetic modifier loci using functional gene networks, '''''Genome Research''''', 20:1143-1153(2010) . co-corresponding author [http://www.ncbi.nlm.nih.gov/pubmed/20538624 pubmed] [[media:Publications_020.pdf|pdf]]

*19. '''Insuk Lee*''', Bindu Ambaru, Pranjali Thakkar, Edward M Marcotte*, Seung Y Rhee*, Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana, '''''Nature Biotechnology''''', 28:149-156 (2010). ''co-corresponding author'' [http://www.ncbi.nlm.nih.gov/pubmed/20118918 pubmed] [[media:Publications_019.pdf|pdf]]
==2009==
*18. '''Insuk Lee''' and Edward Marcotte. Effects of functional bias on supervised learning of a gene network model. '''In Methods in Molecular Biology''' Vol. 541, Computational Systems Biology (ed. R. Ireton, K. Montgomery, J. McDermott, R. Samudrala, R. Bumgarner). Totowa, THE HUMANA. p463-475 (2009) [http://www.ncbi.nlm.nih.gov/pubmed/19381535 pubmed] [[media:Publications_018.pdf|pdf]]

*17. Zhihua Li, '''Insuk Lee''', Emily Moradi, Nai-Jung Hung, Arlen W. Johnson, Edward M. Marcotte, Rational Extension of the Ribosome Biogenesis Pathway Using Network-Guided Genetics, '''''PLoS Biology''''', 7(10):e1000213 (2009) [http://www.ncbi.nlm.nih.gov/pubmed/19806183 pubmed] [[media:Publications_017.pdf|pdf]]

*16. Ryan S. Gray, Philip B. Abitua, Bogdan J. Wlodarczyk, Heather L. Szabo-Rogers, Otis Blanchard, '''Insuk Lee''', Greg S. Weiss, Karen J. Liu, Edward M. Marcotte, John B. Wallingford, Richard H. Finnell. The planar cell polarity effector protein Fuz is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development, '''''Nature Cell Biology''''' 11:1225-32 (2009) '''''*Cover story''''' [http://www.ncbi.nlm.nih.gov/pubmed/19767740 pubmed] [[media:Publications_016.pdf|pdf]]
==2008==
*15. Ben Lehner* and '''Insuk Lee*'''. Network-guided genetic screening: building, testing, and using gene networks to predict gene function. '''''Brief. Funct. Genomic'''''. 7:217-227 (2008). '''''co-corresponding author''''' [http://www.ncbi.nlm.nih.gov/pubmed/18445637 pubmed] [[media:Publications_015.pdf|pdf]]

*14. '''Insuk Lee''' and Edward Marcotte. Integrating Functional Genomics Data. '''In Methods in Molecular Biology''' Vol. 453, Bioinformatics Vol. II (ed. Jonathan Keith). Totowa, THE HUMANA. p267-278 (2008) [http://www.ncbi.nlm.nih.gov/pubmed/18712309 pubmed] [[media:Publications_014.pdf|pdf]]

*13. '''Insuk Lee''', Ben Lehner, Catriona Crombie, Wendy Wong, Andrew G. Fraser, Edward M. Marcotte. A single gene network accurately predicts phenotypic effects of gene perturbation in ''Caenorhabditis elegans''. '''''Nature Genetics''''' 40:181-188 (2008). '''''*Cover story''''' [http://www.ncbi.nlm.nih.gov/pubmed/18223650 pubmed] [[media:Publications_013.pdf|pdf]] This paper was the subject of the following commentary (Natalie de Souza, Networking on organism. Nature Methods 5:217), and minireviews (Von Stetina S. E. and Mango S. E. Wormnet: a crystal ball for Caenorhabditis elegans. Genome Biology 9:226. Borgwardt K. Predicting phenotypic effects of gene perturbations in C. elegans using an integrated network model. BioEssays 30:707)

==Before 2007==
*12. '''Insuk Lee''', Rammohan Narayanaswamy, Edward Marcotte. Bioinformatic prediction of yeast gene function. '''In METHOD IN MICROBIOLOGY''' Vol. 36, Yeast Gene Analysis (ed. Ian Stansfield and Mike Stark), Elsevier. p597-628, (2007) [[media:Publications_012.pdf|pdf]]

*11. Kris McGary, '''Insuk Lee''', Edward M. Marcotte. Broad network-based predictability of S. cerevisiae gene loss-of-function phenotypes. '''''Genome Biology''''' 8:R258 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/18053250 pubmed] [[media:Publications_011.pdf|pdf]]

*10. '''Insuk Lee''', Zhihua Li, and Edward M. Marcotte. An improved bias-reduced probabilistic functional gene network of baker’s yeast ''Saccharomyces cerevisiae''. '''''PLOS One''''' 2:e988 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/17912365 pubmed] [[media:Publications_010.pdf|pdf]]

*9. Hart G. Traver, '''Insuk Lee''', Edward Marcotte. A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality. '''''BMC Bioinformatic''''' 8:236 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/17605818 pubmed] [[media:Publications_009.pdf|pdf]]

*8. Insuk Lee, Shailesh V. Date, Alex T. Adai, Edward Marcotte. A Probabilistic functional network of yeast genes. '''''Science''''' 306:1555-1558, (2004) [http://www.ncbi.nlm.nih.gov/pubmed/15567862 pubmed] [[media:Publications_008.pdf|pdf]]

*7. Bork, P., Jensen, L.J., Von Mering, C., Ramani, A.K., '''Lee I''', Marcotte, E.M. Protein interaction networks from yeast to human. '''''Curr. Opin. Struct. Biol.''''' 14:292-9, (2004) [http://www.ncbi.nlm.nih.gov/pubmed/15193308 pubmed] [[media:Publications_007.pdf|pdf]]

*6. '''Insuk Lee''' and Rasika Harshey. Patterns of Sequence conservation at termini of LTR retrotransposons and DNA transposons in the human genome: Lessons from phage Mu. '''''Nucleic Acids Res.''''' 31:4531-4540, (2003)

*5. '''Insuk Lee''' and Rasika Harshey. The conserved CA/TG motif at Mu termini: T specifies stable transpososome assembly. '''''J. Mol. Biol.''''' 330:261-275, (2003)

*4. '''Insuk Lee''' and Rasika Harshey. Importance of the conserved CA dinucleotide at Mu termini. '''''J. Mol. Biol.''''' 314:433-444, (2001)

*3. Xue, Y., Bai, X., '''Lee, I.''', Kallstrom, G., Ho, J., Brown, J., Stevens, A., and Johnson, A. W. Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. '''''Mol. Cell. Biol.''''' 20:4006-4015, (2000)

*2. Liu, J., Gong, Y., Prakash, O., Wen, L., '''Lee, I'''., Huang J.,-K., and Krishnamoorthi, R. NMR studies of internal dynamics of serine proteinase protein inhibitors: Binding region mobilities of intact and reactive-site hydrolyzed CMTI-III of the squash family and comparison with those of counterparts of CMTI-V of the potato I family. '''''Protein Science''''' 7:132-141, (1998)

*1. Wen, L., '''Lee, I.''', Chen, G., Huang, J.,-K., Gong, Y., and Krishnamoorthi, R. Changing the inhibitory specificity and function of CMTI-V by site-directed mutagenesis. '''''Biochem. Biophys. Res. Commun.''''' 207:897-902, (1995)

Publications

2013-11-29T04:40:01Z

Espjun: /* 2013 */

*[http://scholar.google.com/citations?user=3uHQIOkAAAAJ Google Scholar citation report]
{{#widget:AddHtml
|content=<a title="Insuk Lee's Profile" href='http://www.researcherid.com/rid/F-7722-2010' target='_blank'><img src='http://labs.researcherid.com/mashlets/badge/rid-idsymbol4.gif' border='0'></a>
}}

* '*' co-corresponding authorship
==2013==
*33. Junha Shin, Tak Lee, Hanhae Kim and '''Insuk Lee''', Complementarity between distance- and probability-based methods of gene neighbourhood identification for pathway reconstruction '''''Mol. BioSyst.''''', 2014, 10 (1), 24 - 29., (2013) [http://www.ncbi.nlm.nih.gov/pubmed/24194096 Pubmed][http://pubs.rsc.org/en/content/articlepdf/2014/mb/c3mb70366e pdf]
*32. Eiru Kim, Hanhae Kim and '''Insuk Lee''', JiffyNet: a web-based instant protein network modeler for newly sequenced species. '''''Nucleic Acids Research''''' 41 (W1): W192-W197., (2013) [http://www.ncbi.nlm.nih.gov/pubmed/23685435 Pubmed][http://nar.oxfordjournals.org/content/early/2013/05/17/nar.gkt419.full.pdf+html pdf]
*31. '''Insuk Lee''', Network approaches to the genetic dissection of phenotypes in animals and humans. '''''Animal Cells and Systems''''' Vol.17,No.2,75-79(2013)[http://www.tandfonline.com/doi/abs/10.1080/19768354.2013.789076 Link]

==2012==
*30. Peggy I Wang, Sohyun Hwang, Rodney P Kincaid, Christopher S Sullivan, '''Insuk Lee*''', and Edward M Marcotte*. RIDDLE: Reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network. '''''Genome Biology''''' 13:R125 (2012)[http://www.ncbi.nlm.nih.gov/pubmed/23268829 pubmed]
*29. Lee Chae*, '''Insuk Lee*''', Junha Shin, and Seung Yon Rhee*. Towards understanding how molecular networks evolve in plant. '''''Current Opinion in Plant Biology''''' 15:177-184 (2012)[http://www.ncbi.nlm.nih.gov/pubmed/22280840 pubmed] [[media:CurrOpinPlantBiol 15-177.pdf|pdf]]
*28. Stephanie M. Quanbeck, Libuse Brachova, Alexis A. Campbell, Xin Guan, Ann Perera, Kun He, Seung Y. Rhee, Preeti Bais, Julie A. Dickerson, Philip Dixon, Gert Wohlgemuth, Oliver Fiehn, Lenore Barken, Iris Lange, B. Markus Lange, '''Insuk Lee''', Diego Cortes, Carolina Salazar, Joel Shuman, Vladimir Shulaev, David V. Huhman, Lloyd W. Sumner, Mary R. Roth, Ruth Welti, Hilal Ilarslan, Eve S. Wurtele, and Basil J. Nikolau. Metabolomics as a hypothesis-generating functional genomics tool for the annotation of Arabidopsis thaliana genes of “unknown function”. '''''Frontiers in Plant Science''''' 3:1-12 (2012) [http://www.ncbi.nlm.nih.gov/pubmed/22645570/ pubmed][[media:Fpls-03-00015.pdf|pdf]]

==2011==
*27. '''Insuk Lee*''', Young-Su Seo, Dusica Coltrane, Sohyun Hwang, Taeyun Oh, Edward M. Marcotte*, and Pamela C. Ronald*. Genetic dissection of the biotic stress response using a genome-scale gene network for rice. '''''PNAS''''' 108(45):18548-53 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/22042862 pubmed] [[media:PNAS-2011-Lee-18548-53.pdf|pdf]]

*26. Sohyun Hwang, Seung Y. Rhee*, Edward M. Marcotte*, and '''Insuk Lee*'''. Systematic prediction of candidate gene function associated to phenotype traits using the probabilistic functional gene network of Arabidopsis thaliana. '''''Nature Protocols''''' 6:1429-1442 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21886106 pubmed][[media:2011.08.25.online.nprot.2011.372.pdf|pdf]]

*25. '''Insuk Lee''', Probabilistic functional gene societies. '''''Progress in Biophysics and Molecular Biology''''' 106:435-442 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21281658 pubmed] [[media:Publications_023_n.pdf|pdf]]

*24. '''Insuk Lee*''', U. Martin Blom, Peggy I. Wang, Jung Eun Shim, and Edward M. Marcotte*. Prioritizing candidate disease genes by network-based boosting of genome-wide association data. '''''Genome Research''''' 21:1109-1121 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21536720 pubmed] [[media:Publications_025_n.pdf|pdf]]

*23. Young-Su Seo, Mawsheng Chern, Laura E. Bartley, Muho Han, Ki-Hong Jung, '''Insuk Lee''', Harkamal Walia, Todd Richter, Xia Xu, Peijian Cao, Wei Bai, Rajeshwari Ramanan, Fawn Amonpant, Loganathan Arul, Patrick E. Canlas, Randy Ruan, Chang-Jin Park, Xuewel Chen, Sohyun Hwang, Jong-Seong Jeon, and Pamela C. Ronald. Towards establishment of a rice stress response interactome. '''''PLoS Genetics''''' 7(4):e1002020 (2011) [http://www.ncbi.nlm.nih.gov/pubmed/21533176 pubmed] [[media:Publications_024.pdf|pdf]]

==2010==
*22. Ni Huang, '''Insuk Lee''', Edward M.Marcotte, Matthew E.Hurles, Characterising and predicting haploinsufficiency in the human genome, '''''PLoS Genet.''''' 6(10):e1001154(2010) [http://www.ncbi.nlm.nih.gov/pubmed/20976243 pubmed] [[media:Publications_022.pdf|pdf]]

*21. Eiru Kim, Jaeyoon Shin and '''Insuk Lee''', Assessment of effectiveness of the network-guided genetic screen, '''''Mol Biosyst.''''' 6:1803-1806(2010) [http://www.ncbi.nlm.nih.gov/pubmed/20697632 pubmed] [[media:Publications_021.pdf|pdf]]

*20. '''Insuk Lee*''', Ben Lehner, Tanya Vavouri, Junha Shin, Andrew G. Fraser, and Edward M. Marcotte, Predicting genetic modifier loci using functional gene networks, '''''Genome Research''''', 20:1143-1153(2010) . co-corresponding author [http://www.ncbi.nlm.nih.gov/pubmed/20538624 pubmed] [[media:Publications_020.pdf|pdf]]

*19. '''Insuk Lee*''', Bindu Ambaru, Pranjali Thakkar, Edward M Marcotte*, Seung Y Rhee*, Rational association of genes with traits using a genome-scale gene network for Arabidopsis thaliana, '''''Nature Biotechnology''''', 28:149-156 (2010). ''co-corresponding author'' [http://www.ncbi.nlm.nih.gov/pubmed/20118918 pubmed] [[media:Publications_019.pdf|pdf]]
==2009==
*18. '''Insuk Lee''' and Edward Marcotte. Effects of functional bias on supervised learning of a gene network model. '''In Methods in Molecular Biology''' Vol. 541, Computational Systems Biology (ed. R. Ireton, K. Montgomery, J. McDermott, R. Samudrala, R. Bumgarner). Totowa, THE HUMANA. p463-475 (2009) [http://www.ncbi.nlm.nih.gov/pubmed/19381535 pubmed] [[media:Publications_018.pdf|pdf]]

*17. Zhihua Li, '''Insuk Lee''', Emily Moradi, Nai-Jung Hung, Arlen W. Johnson, Edward M. Marcotte, Rational Extension of the Ribosome Biogenesis Pathway Using Network-Guided Genetics, '''''PLoS Biology''''', 7(10):e1000213 (2009) [http://www.ncbi.nlm.nih.gov/pubmed/19806183 pubmed] [[media:Publications_017.pdf|pdf]]

*16. Ryan S. Gray, Philip B. Abitua, Bogdan J. Wlodarczyk, Heather L. Szabo-Rogers, Otis Blanchard, '''Insuk Lee''', Greg S. Weiss, Karen J. Liu, Edward M. Marcotte, John B. Wallingford, Richard H. Finnell. The planar cell polarity effector protein Fuz is essential for targeted membrane trafficking, ciliogenesis, and mouse embryonic development, '''''Nature Cell Biology''''' 11:1225-32 (2009) '''''*Cover story''''' [http://www.ncbi.nlm.nih.gov/pubmed/19767740 pubmed] [[media:Publications_016.pdf|pdf]]
==2008==
*15. Ben Lehner* and '''Insuk Lee*'''. Network-guided genetic screening: building, testing, and using gene networks to predict gene function. '''''Brief. Funct. Genomic'''''. 7:217-227 (2008). '''''co-corresponding author''''' [http://www.ncbi.nlm.nih.gov/pubmed/18445637 pubmed] [[media:Publications_015.pdf|pdf]]

*14. '''Insuk Lee''' and Edward Marcotte. Integrating Functional Genomics Data. '''In Methods in Molecular Biology''' Vol. 453, Bioinformatics Vol. II (ed. Jonathan Keith). Totowa, THE HUMANA. p267-278 (2008) [http://www.ncbi.nlm.nih.gov/pubmed/18712309 pubmed] [[media:Publications_014.pdf|pdf]]

*13. '''Insuk Lee''', Ben Lehner, Catriona Crombie, Wendy Wong, Andrew G. Fraser, Edward M. Marcotte. A single gene network accurately predicts phenotypic effects of gene perturbation in ''Caenorhabditis elegans''. '''''Nature Genetics''''' 40:181-188 (2008). '''''*Cover story''''' [http://www.ncbi.nlm.nih.gov/pubmed/18223650 pubmed] [[media:Publications_013.pdf|pdf]] This paper was the subject of the following commentary (Natalie de Souza, Networking on organism. Nature Methods 5:217), and minireviews (Von Stetina S. E. and Mango S. E. Wormnet: a crystal ball for Caenorhabditis elegans. Genome Biology 9:226. Borgwardt K. Predicting phenotypic effects of gene perturbations in C. elegans using an integrated network model. BioEssays 30:707)

==Before 2007==
*12. '''Insuk Lee''', Rammohan Narayanaswamy, Edward Marcotte. Bioinformatic prediction of yeast gene function. '''In METHOD IN MICROBIOLOGY''' Vol. 36, Yeast Gene Analysis (ed. Ian Stansfield and Mike Stark), Elsevier. p597-628, (2007) [[media:Publications_012.pdf|pdf]]

*11. Kris McGary, '''Insuk Lee''', Edward M. Marcotte. Broad network-based predictability of S. cerevisiae gene loss-of-function phenotypes. '''''Genome Biology''''' 8:R258 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/18053250 pubmed] [[media:Publications_011.pdf|pdf]]

*10. '''Insuk Lee''', Zhihua Li, and Edward M. Marcotte. An improved bias-reduced probabilistic functional gene network of baker’s yeast ''Saccharomyces cerevisiae''. '''''PLOS One''''' 2:e988 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/17912365 pubmed] [[media:Publications_010.pdf|pdf]]

*9. Hart G. Traver, '''Insuk Lee''', Edward Marcotte. A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality. '''''BMC Bioinformatic''''' 8:236 (2007) [http://www.ncbi.nlm.nih.gov/pubmed/17605818 pubmed] [[media:Publications_009.pdf|pdf]]

*8. Insuk Lee, Shailesh V. Date, Alex T. Adai, Edward Marcotte. A Probabilistic functional network of yeast genes. '''''Science''''' 306:1555-1558, (2004) [http://www.ncbi.nlm.nih.gov/pubmed/15567862 pubmed] [[media:Publications_008.pdf|pdf]]

*7. Bork, P., Jensen, L.J., Von Mering, C., Ramani, A.K., '''Lee I''', Marcotte, E.M. Protein interaction networks from yeast to human. '''''Curr. Opin. Struct. Biol.''''' 14:292-9, (2004) [http://www.ncbi.nlm.nih.gov/pubmed/15193308 pubmed] [[media:Publications_007.pdf|pdf]]

*6. '''Insuk Lee''' and Rasika Harshey. Patterns of Sequence conservation at termini of LTR retrotransposons and DNA transposons in the human genome: Lessons from phage Mu. '''''Nucleic Acids Res.''''' 31:4531-4540, (2003)

*5. '''Insuk Lee''' and Rasika Harshey. The conserved CA/TG motif at Mu termini: T specifies stable transpososome assembly. '''''J. Mol. Biol.''''' 330:261-275, (2003)

*4. '''Insuk Lee''' and Rasika Harshey. Importance of the conserved CA dinucleotide at Mu termini. '''''J. Mol. Biol.''''' 314:433-444, (2001)

*3. Xue, Y., Bai, X., '''Lee, I.''', Kallstrom, G., Ho, J., Brown, J., Stevens, A., and Johnson, A. W. Saccharomyces cerevisiae RAI1 (YGL246c) is homologous to human DOM3Z and encodes a protein that binds the nuclear exoribonuclease Rat1p. '''''Mol. Cell. Biol.''''' 20:4006-4015, (2000)

*2. Liu, J., Gong, Y., Prakash, O., Wen, L., '''Lee, I'''., Huang J.,-K., and Krishnamoorthi, R. NMR studies of internal dynamics of serine proteinase protein inhibitors: Binding region mobilities of intact and reactive-site hydrolyzed CMTI-III of the squash family and comparison with those of counterparts of CMTI-V of the potato I family. '''''Protein Science''''' 7:132-141, (1998)

*1. Wen, L., '''Lee, I.''', Chen, G., Huang, J.,-K., Gong, Y., and Krishnamoorthi, R. Changing the inhibitory specificity and function of CMTI-V by site-directed mutagenesis. '''''Biochem. Biophys. Res. Commun.''''' 207:897-902, (1995)

People:JH Shin

2013-11-06T06:15:22Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* Hanhae Kim, '''Junha Shin''', Eiru Kim, Hyojin Kim, Sohyun Hwang, Jung Eun Shim and Insuk Lee. YeastNet v3: a public database of data-specific and integrated functional gene networks for Saccharomyces cerevisiae, ''Nucleic Acids Research'',
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte. Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20(8), pp1143-1153 (2010)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412(3), pp454-459 (2011)''

File:People Junha Shin.jpg

2012-04-02T07:07:11Z

Espjun: uploaded a new version of "File:People Junha Shin.jpg"

Portrait of Junha Shin

People:JH Shin

2012-03-24T02:26:39Z

Espjun: /* Publications */

__NOTOC__
{|
|[[File:People_Junha_Shin.jpg|150px]]
|
===Junha Shin===
*'''Ph.D candidate''', Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biotechnology (09/2008 – Now)
Theme : Systems / Network Biology
*Combined master’s and doctorate program, ''Yonsei university'', Dept. of Biology (03/2005 – 08/2008)
Advisor: Prof. Tae H. Lee 
Theme : Molecular Biological / Proteomic analysis of modifications and functions of IAPs and NF-κB in human cancer cells
*'''B.S''', ''Yonsei University'', Dept. of Biology (03/1998 – 02/2005, ''mandatory military service'' : 06/2000 – 08/2002)
|}

==Current Research Interests==
*Systems biology, Data mining and interpretation of biological themes.
*Gene network construction and analysis for various model organisms.

==Other (Research) Interests==
*Interpretation of genetic interactions and epistasis.
*Interpretation and remedy of autoimmune diseases.
*All that artistic and intellectual things.

==Publications==
* Lee Chae, Insuk Lee, '''Junha Shin''', and Seung Yon Rhee. Towards understanding how molecular networks evolve in plant. ''Current Opinion in Plant Biology'', ''15:1-8 (2012)''
* Insuk Lee, Ben Lehner, Tanya Vavouri, '''Junha Shin''', Andrew G. Fraser, and Edward M. Marcotte, Predicting genetic modifier loci using functional gene networks. ''Genome Research'', ''20(8), pp1143-1153 (2010)''
* Hyung-Seung Jin, Hyung-Sun Park, '''Jun-Ha Shin''', Dong-Hwan Kim, Sung-Hun Jun, Chang-Jun Lee, and Tae H. Lee. A novel inhibitor of apoptosis protein (IAP)-interacting protein, Vestigial-like (Vgl)-4, counteracts apoptosis-inhibitory function of IAPs by nuclear sequestration. ''Biochemical and Biophysical Research Communications'', ''412(3), pp454-459 (2011)''

People:JH Shin

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