People:YH Ko

Postdoctoral researcher, Department of Biotechnology, Yonsei University (10/2011 ~ Present)
Postdoctoral researcher, Institute for Genomics Biology, University of Illinois at Urbana-Champaign, (01/2011 ~ 08/2011)
PhD in Computer Science, University of Illinois at Urbana-Champaign, 2010
- Advisor: Prof. ChengXiang Zhai, Department of Computer Science
- Co-Advisor: Prof. Sandra Rodriguez-Zas, Department of Animal Science
- Co-Advisor: Prof. Nathan Price, Department of Chemical and Biomolecular Engineering
M.S. in CSE, Korea University, 2003
- Advisor: Prof. Hyeoncheol Kim
B.S. in CSE, Korea University, 2001

Current Research Interests

Systems Biology and computational biology
- Transcriptional Regulation Network, Cell type identification and analysis of network morphology of Human Brain, Immune cell responses from viral infection
Biological data mining and data integration

Book Chapter

S. L. Rodriguez-Zas, Y. Ko. Applied Statistics for Network Biology: Methods in Systems Biology,

Chapter: Elucidation of General and Condition-dependent Gene Pathways Using Mixture Models and Bayesian Networks. Wiley, 91-103, 2011.

Journal Articles

Y. Ko, S. A. Ament, J. A. Eddy, J. Cabellero, J. C. Earls, L. Hood and N. D. Price. Cell-type specific genes show striking and distinct patterns of spatial expression in the mouse brain. PNAS 110(8):3095-3100 (2013) pubmed pdf
J. C. Earls, J. A. Eddy, C. Funk, Y. Ko, A. Magis, and N .D. Price, AUREA: An open-source software system for accurate and user-friendly identification of relative expression molecular signatures, (Accepted to BMC Bioinformatics, 2013)
A. Magis, J. Earls, Y. Ko, J. Eddy and N. Price. Graphics processing unit implementations of relative expression analysis algorithms enable dramatic computational speedup, Bioinformatics, 2011
Y. Ko, C.Zhai and S. L. Rodriguez-Zas. Discovery of variation in the co-expression patterns of gene pathways across biological replicates, IJBRA, 2010
Y. Ko, C.Zhai and S. L. Rodriguez-Zas. Inference of gene pathways using mixture Bayesian networks, BMC Systems Biology, 3:54, 2009 Marked as highly accessed
S. L. Rodriguez-Zas, Y. Ko, H. A. Adams and B. R. Southey. Advancing the understanding of the embryo transcriptome co-regulation using meta-, functional, and gene network analysis tools, Reproduction,135:213-224, 2008
Y. Ko, H. Kim and W. Lee. Frequent Itemset Search Using LSI Similarity, Journal of Korean Association of Computer Education, 6:2, 2003

Referred Conference Papers

S. Kim, J. Kim, Y. Ko, S. Hwang and J. Han.PerRank:Personalized Rank Retrieval with Categorical and Numerical Attributes, WAIM, 2008
Y. Ko, C. Zhai and S. L. Rodriguez-Zas. Inference of Gene Pathways using Gaussian Mixture Models, IEEE BIBM, 2007
Y. Ko, H. Kim. An effcient algorithm to search frequent itemsets using TID Lists, KISS, 2002
Y. Ko, H. Kim and W. Lee. Design and Implementation of a XML Editor For DataBases, KISS, 2001