People:IS Lee

	Insuk Lee Department of Biotechnology College of Life Science and Biotechnology 134 Shinchon-dong, Seodaemun-gu, Seoul 120-749, Korea Office: +82-2-2123-5559 Email: insuklee@yonsei.ac.kr or insuksysbio@gmail.com URL: http://polaris.icmb.utexas.edu/people/il1001/index.htm

EDUCATION

• Postdoctoral Work, University of Texas at Austin, TX (01/2003 – 02/2008)
  Research Advisor: Prof. Edward M. Marcotte
  Biological network modeling and analysis for genotype-phenotype mapping
• Ph.D., University of Texas at Austin, TX (09/1996 – 12/2002)

Major: Molecular genetics & Microbiology Advisor: Prof. Rasika M. Harshey Dissertation: Importance of the Conserved TG/CA Dinucleotide Termini in Phage Mu Transposition: Similarities to Transposable Elements in the Human Genome

• Texas State University at San Marcos, TX (06/2000 – 12/2002)

Complete 37 (31 undergraduate, 6 graduate) credit hours in Computer Science

• M.S., Western Illinois University, Macomb, IL (09/1993 – 05/1996)

Major: Biology Advisor: Prof. Thomas Alton Thesis: Genetic analysis of Agrobacterium vir region by generating gene fusion using bacterial transposon

• B.S., Hanyang University, Seoul, Korea (03/1986 – 02/1993, military service: 02/1988 – 05/1990)

Major: Biology

RESEARCH EXPERIENCE

• Assistant Professor (03/2008 – present), Department of Biotechnology, Yonsei University, Seoul, Korea. Probabilistic functional gene network for Arabidopsis, human, and Rice.

• Research Associate (09/2006 – 02/2008), Post-doctoral fellow (01/2003 – 08/2006), Center for Systems and Synthetic Biology, University of Texas at Austin. Biological data mining from various genomics and proteomics data, integration biological data into gene/protein network models, cellular system analysis by network topology, comparative network analysis (biological, social, internet), prediction of gene functions, phenotypic change prediction, probabilistic gene network modeling for yeast and C. elegans.

• Graduate research assistant (09/1996 – 12/2002), Department of Microbiology, University of Texas at Austin, Developed sensitive, plasmid-based assay system to monitor Mu transposition in vivo, biochemical/genetic study of functional roles of highly conserved terminal dinucleotides of Mu, computational analysis of conserved terminal sequences of transposable-like elements in human genome

• Graduate student (09/1993 – 05/1996), Department of Biology, Western Illinois University, Macomb, IL. Transposon mutagenesis and Expression analysis in the virulent gene virD region of Agrobacterium Tumefaciens.

• Research assistant (01/1994 – 08/1995), Department of Chemistry, Western Illinois University, Macomb, IL. Analysis of the inhibitory specificity and function of Cucurbita maxima trypsin inhibitor (CMTI)-V by site-directed mutagenesis, Cloning/expression/purification of CMTI-III and blood coagulation factor XIIa.

TEACHING EXPERIENCE

• Biochemistry (BTE2102—undergraduate-level course), Yonsei University, Korea (2008-2009)
• Introduction to Modern Biochemistry (team teaching, bioinformatics and genomics section), Yanbian *University of Science and Technology, China (2008, 2009)
• Bioinformatics (BTE4402—upper-level undergraduate course, BTE7240—graduate-level course), Yonsei University, Korea (2008-2009)
• Microbiology Laboratory Course (MIC129K, undergraduate-level), University of Texas at Austin, USA (1997, 2000)

AFFILIATIONS AND HONORS

• Member of International Society for Computational Biology (ISCB)
• Intelligent Systems for Molecular Biology (ISMB) Travel Fellowship Award, 2006
• National Institute of General Medicine Science (NIGMS) Scholarship for Keystone Symposia of Systems Biology, 2006
• Intelligent Systems for Molecular Biology (ISMB) Travel Fellowship Award, 2005
• The L. Joe Berry Memorial Scholarship, University of Texas at Austin, 2001
• David Bruton, Jr. Fellowship, University of Texas at Austin, 2000
• Korean Honor Scholarship from Embassy of the Republic of Korea in the U.S., 1999
• The Hal H. Ramsey, III Memorial Scholarship, University of Texas at Austin, 1999
• Academic Achievement Scholarship, Hanyang University, 1986, 1991, 1992

PROFESSIONAL SERVICE AND EXPERIENCE

• Journal Reviewing: Ad hoc reviewer for Genome Research, Genome Biology, Bioinformatics, BioTechniques, and INFORMS Journal on Computing.
• Program Committee of ACM Third International Workshop on Data and Text Mining in Bioinformatics (2009)
• Long-term sponsored participant, Institute of Pure and Applied Mathematics (IPAM) Special Semester on “Proteomics: Sequence, Structure, Function”, University of California at Los Angelis, Spring 2004
• Sponsored participant, Institute of Pure and Applied Mathematics (IPAM) short program “Sequence Analysis *Toward System Biology”, University of California at Los Angelis, Jan 2006
• Sponsored participant, Institute of Pure and Applied Mathematics (IPAM) short program “System Biology and Molecular Modeling”, University of California at Los Angelis, May 2006