Difference between revisions of "Domain2Pathway by Pathway Specificity (PS)"
From Bioinformatics Lab
(Created page with "Protein domains are basic functional units of proteins, yet domain-based pathway annotations for proteins are still challenging tasks because many domains are pervasive among ...") |
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| − | '''''Citation''''' : Jung Eun Shim, Ji Hyun Kim, Junha Shin, Ji Eun Lee and Insuk Lee, Network-based identification of pathway-specific protein domains and their implications for human diseases | + | '''''Citation''''' : Jung Eun Shim, Ji Hyun Kim, Junha Shin, Ji Eun Lee and Insuk Lee, Network-based identification of pathway-specific protein domains and their implications for human diseases '''(under review)''' |
'''''Contact Information''''' : Insuk Lee (insuklee[at]yonsei[dot]ac[dot]kr) | '''''Contact Information''''' : Insuk Lee (insuklee[at]yonsei[dot]ac[dot]kr) | ||
Revision as of 15:56, 22 September 2017
Protein domains are basic functional units of proteins, yet domain-based pathway annotations for proteins are still challenging tasks because many domains are pervasive among diverse pathways. Nevertheless, some domains may exist in specific pathways. We therefore developed a network-based scoring scheme to quantify specificity of domain-pathway associations, and then used it to classify 'pathway-specific domains (PSDs)' and 'non-specific domains (NSDs)'.
Citation : Jung Eun Shim, Ji Hyun Kim, Junha Shin, Ji Eun Lee and Insuk Lee, Network-based identification of pathway-specific protein domains and their implications for human diseases (under review)
Contact Information : Insuk Lee (insuklee[at]yonsei[dot]ac[dot]kr)
