Difference between revisions of "PS"

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(Created page with "Protein domains are basic functional units of proteins, yet domain-based pathway annotations for proteins are still challenging tasks because many domains are pervasive among ...")
 
 
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Protein domains are basic functional units of proteins, yet domain-based pathway annotations for proteins are still challenging tasks because many domains are pervasive among diverse pathways.
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#REDIRECT [[Domain2Pathway by Pathway Specificity (PS)]]
Nevertheless, some domains may exist in specific pathways.
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We therefore developed a network-based scoring scheme to quantify '''specificity of domain-pathway associations''', and then used it to classify ''''pathway-specific domains (PSDs)'''' and ''''non-specific domains (NSDs)''''.
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*[http://www.netbiolab.org/wiki/images/0/09/WMI_program.zip Source codes for PS calculation]
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*[http://www.netbiolab.org/wiki/images/1/1e/SC_WMI_12K.txt Example datafile]
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'''''Citation''''' : Jung Eun Shim, Ji Hyun Kim, Junha Shin, Ji Eun Lee and Insuk Lee, Network-based identification of pathway-specific protein domains and their implications for human diseases
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'''''Contact Information''''' : Insuk Lee (insuklee[at]yonsei[dot]ac[dot]kr)
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Latest revision as of 15:55, 22 September 2017

  1. REDIRECT Domain2Pathway by Pathway Specificity (PS)
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