Difference between revisions of "Journal Club"

Revision as of 20:52, 1 July 2022

2022-1st semester scOmics
Date	Team	Paper index	Presenter	Paper title
2022/08/11	Single-cell	22-44	IS Choi	Biologically informed deep learning to infer gene program activity in single cells
2022/08/04	Single-cell	22-43	SB Baek	SIMBA: SIngle-cell eMBedding Along with features
2022/07/28	Single-cell	22-42	JH Cha	Mapping single-cell data to reference atlases by transfer learning
2022/07/21	Single-cell	22-41	JW Yu	Pan-cancer mapping of single T cell profiles reveals a TCF1:CXCR6-CXCL16 regulatory axis essential for effective anti-tumor immunity
2022/07/14	Single-cell	22-40	IS Choi	Identifying disease-critical cell types and cellular processes across the human body by integration of single-cell profiles and human genetics
2022/07/07	Single-cell	22-39	EJ Sung	Metacells untangle large and complex single-cell transcriptome networks MetaCell: analysis of single-cell RNA-seq data using K-nn graph partitions Metacell‑2: a divide‑and‑conquer metacell algorithm for scalable scRNA‑seq analysis
2022/06/23	Single-cell	22-38	SB Baek	Co-varying neighborhood analysis identifies cell populations associated with phenotypes of interest from single-cell transcriptomics
2022/06/09	Single-cell	22-37	JH Cha	Integrating T cell receptor sequences and transcriptional profiles by clonotype neighbor graph analysis (CoNGA)
2022/06/02	Single-cell	22-36	JW Yu	Hepatocellular carcinoma patients with high circulating cytotoxic T cells and intra-tumoral immune signature benefit from pembrolizumab: results from a single-arm phase 2 trial
2022/05/19	Single-cell	22-35	EJ Sung	Effect of imputation on gene network reconstruction from single-cell RNA-seq data
2022/05/12	Single-cell	22-34	IS Choi	Diagnostic Evidence GAuge of Single cells (DEGAS): a flexible deep transfer learning framework for prioritizing cells in relation to disease
2022/04/07	Single-cell	22-33	SB Baek	Integrating single-cell sequencing data with GWAS summary statistics reveals CD16+monocytes and memory CD8+T cells involved in severe COVID-19
2022/03/25	Single-cell	22-32	JH Cha	Single cell T cell landscape and T cell receptor repertoire profiling of AML in context of PD-1 blockade therapy
2022/03/18	Single-cell	22-31	JW Yu	Systematic investigation of cytokine signaling activity at the tissue and single-cell levels
2022/03/04	Single-cell	22-30	EJ Sung	Neoantigen-driven B cell and CD4 T follicular helper cell collaboration promotes anti-tumor CD8 T cell responses

2022-1st semester Microbiome
Date	Team	Paper index	Presenter	Paper title
2022/09/22	Microbiome	22-38	SH Ahn	Identification of shared and disease-specific host gene–microbiome associations across human diseases using multi-omic integration
2022/09/15	Microbiome	22-38	HJ Kim	Caudovirales bacteriophages are associated with improved executive function and memory in flies, mice, and humans
2022/09/08	Microbiome	22-37	JH Cha	A randomized controlled trial for response of microbiome network to exercise and diet intervention in patients with nonalcoholic fatty liver disease
2022/09/01	Microbiome	22-36	NY Kim	Discovery of bioactive microbial gene products in inflammatory bowel disease
2022/08/25	Microbiome	22-35	JY Ma	Identification of antimicrobial peptides from the human gut microbiome using deep learning
2022/08/18	Microbiome	22-34	SH Lee	Large-scale microbiome data integration enables robust biomarker identification
2022/08/11	Microbiome	22-33	SH Ahn	Predicting cancer prognosis and drug response from the tumor microbiome
2022/08/04	Microbiome	22-32	HJ Kim	Thousands of small, novel genes predicted in global phage genomes
2022/07/28	Microbiome	22-31	JH Cha	MetaPop: a pipeline for macro- and microdiversity analyses and visualization of microbial and viral metagenome-derived populations
2022/07/21	Microbiome	22-30	NY Kim	Biosynthetic potential of the global ocean microbiome
2022/07/14	Microbiome	22-29	JY Ma	Compositionally Aware Phylogenetic Beta-Diversity Measures Better Resolve Microbiomes Associated with Phenotype
2022/07/07	Microbiome	22-28	SH Lee	Tutorial: assessing metagenomics software with the CAMI benchmarking toolkit disease Critical Assessment of Metagenome Interpretation: the second round of challenges
2022/06/24	Microbiome	22-27	SH Ann	Identification of Faecalibacterium prausnitzii strains for gut microbiome-based intervention in Alzheimer’s-type dementia
2022/06/10	Microbiome	22-26	HJ Kim	Microbiome and metabolome features of the cardiometabolic disease spectrum
2022/06/03	Microbiome	22-25	JH Cha	Functional and genetic markers of niche partitioning among enigmatic members of the human oral microbiome
2022/05/27	Microbiome	22-24	NY Kim	Integrating phylogenetic and functional data in microbiome studies
2022/05/20	Microbiome	22-23	MY Ma	Pandora: nucleotide-resolution bacterial pan-genomics with reference graphs
2022/05/13	Microbiome	22-22	SH Lee	Multivariable association discovery in population-scale meta-omics studies
2022/04/08	Microbiome	22-21	SH Ahn	Comprehensive Analysis Reveals the Evolution and Pathogenicity of Aeromonas, Viewed from Both Single Isolated Species and Microbial Communities
2022/04/01	Microbiome	22-20	HJ Kim	AGAMEMNON: an Accurate metaGenomics And MEtatranscriptoMics quaNtificatiON analysis suite
2022/03/18	Microbiome	22-19	JH Cha	Metapangenomics of the oral microbiome provides insights into habitat adaptation and cultivar diversity
2022/03/04	Microbiome	22-18	JY Ma	Microbiota of the prostate tumor environment investigated by whole-transcriptome profiling

2022-scOmics
Date	Team	Paper index	Presenter	Paper title
2022/02/25	Single-cell	22-17	SB Baek	MultiMAP: dimensionality reduction and integration of multimodal data
2022/02/18	Single-cell	22-16	IS Choi	CellRank for directed single-cell fate mapping
2022/02/11	Single-cell	22-15	JH Cha	Single-cell analyses reveal key immune cell subsets associated with response to PD-L1 blockade in triple-negative breast cancer
2022/02/04	Single-cell	22-14	IS Choi	Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
2022/01/28	Single-cell	22-13	EJ Sung	Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification
2022/01/28	Single-cell	22-12	JH Cha	Pan-cancer single-cell landscape of tumor-infiltrating T cells
2022/01/14	Single-cell	22-11	JW Yu	Atlas of clinically distinct cell states and ecosystems across human solid tumors
2022/01/07	Single-cell	22-10	SB Baek	Single-cell ATAC and RNA sequencing reveal pre-existing and persistent cells associated with prostate cancer relapse

2022-Microbiome
Date	Team	Paper index	Presenter	Paper title
2022/02/25	Microbiome	22-9	NY Kim	Species-resolved sequencing of low-biomass or degraded microbiomes using 2bRAD-M
2022/02/18	Microbiome	22-8	SH Lee	Microbial co-occurrence complicates associations of gut microbiome with US immigration, dietary intake and obesity
2022/02/11	Microbiome	22-7	SH Ahn	Gut microbial determinants of clinically important improvement in patients with rheumatoid arthritis
2022/02/04	Microbiome	22-6	JH Cha	Gut microbiota modulates weight gain in mice after discontinued smoke exposure
2022/01/28	Microbiome	22-5	JY Ma	The human microbiome encodes resistance to the antidiabetic drug acarbose
2022/01/28	Microbiome	22-4	SH Lee	Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis
2022/01/14	Microbiome	22-3	HJ Kim	The influence of the gut microbiome on BCG-induced trained immunity
2022/01/07	Microbiome	22-2	JY Ma	Towards the biogeography of prokaryotic genes
2022/01/07	Microbiome	22-1	NY Kim	ReprDB and panDB: minimalist databases with maximal microbial representation

2021-2nd semester
Date	Team	Paper index	Presenter	Paper title
2021/11/23	Single-cell	21-39	IS Choi	Chromatin and gene-regulatory dynamics of the developing human cerebral cortex at single-cell resolution
2021/11/16	Single-cell	21-38	SB Back	Single-cell ATAC and RNA sequencing reveal pre-existing and persistent subpopulations of cells associated with relapse of prostate cancer
2021/11/09	Single-cell	21-37	JH Cha	Integrated single-cell transcriptomics and epigenomics reveals strong germinal center-associated etiology of autoimmune risk loci
2021/11/02	Single-cell	21-36	SB Baek	Functional Inference of Gene Regulation using Single-Cell Multi-Omics
2021/10/26	Single-cell	21-35	IS Choi	Single-cell analyses reveal a continuum of cell state and composition changes in the malignant transformation of polyps to colorectal cancer
2021/10/19	Single-cell	21-34	JH Cha	Single-cell sequencing links multiregional immune landscapes and tissue-resident T cells in ccRCC to tumor topology and therapy efficacy
2021/10/05	Single-cell	21-33	JH Cha	Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma
2021/09/28	Single-cell	21-32	SB Baek	Single-cell chromatin accessibility landscape identifies tissue repair program in human regulatory T cells
2021/09/14	Single-cell	21-31	IS Choi	Identification of resistance pathways and therapeutic targets in relapsed multiple myeloma patients through single-cell sequencing
2021/09/07	Single-cell	21-30	JH Cha	A single-cell map of intratumoral changes during anti-PD1 treatment of patients with breast cancer
2021/08/31	Single-cell	21-29	IS Choi	Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma
2021/08/24	Single-cell	21-28	SB Baek	Interpreting type 1 diabetes risk with genetics and single-cell epigenomics

2021-1st semester
Date	Team	Paper index	Presenter	Paper title
2021/06/03	-	21-27	HJ Kim	Massive expansion of human gut bacteriophage diversity
2021/06/03	-	21-26	JY Ma	The infant gut resistome associates with E. coli, environmental exposures, gut microbiome maturity, and asthma-associated bacterial composition
2021/05/27	-	21-25	JK Yoon	Methotrexate impacts conserved pathways in diverse human gut bacteria leading to decreased host immune activation
2021/05/20	-	21-24	NY Kim	A metagenomic strategy for harnessing the chemical repertoire of the human microbiome
2021/05/20	-	21-23	IS Choi	Predictive metabolomic profiling of microbial communities using amplicon or metagenomic sequences
2021/05/13	-	21-22	SA Kim	Gut microbiome structure and metabolic activity in inflammatory bowel disease
2021/05/13	-	21-21	HJ Kim	Microbiome connections with host metabolism and habitual diet from 1,098 deeply phenotyped individuals
2021/05/06	-	21-20	JY Ma	A predictive index for health status using species-level gut microbiome profiling
2021/05/06	-	21-19	JH Cha	Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases
2021/04/29	-	21-18	SB Baek	Gastrointestinal microbiota composition predicts peripheral inflammatory state during treatment of human tuberculosis
2021/04/29	-	21-17	SR You	Structure of the Mucosal and Stool Microbiome in Lynch Syndrome
2021/04/22	-	21-16	HH Eom	Cross-reactivity between tumor MHC class 1-restricted antigens and an enterococcal bacteriophage
2021/04/22	-	21-15	JH Park	Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice
2021/04/15	-	21-14	MH Lee	The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk
2021/04/08	-	21-13	YY Jang	Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
2021/04/01	-	21-12	NY Kim	Personalized Mapping of Drug Metabolism by the Human Gut Microbiome
2021/03/25	-	21-11	JM Lee	Mining the Human Gut Microbiota for Immunomodulatory Organisms
2021/03/18	-	21-10	JH Cha	Microbiome analyses of blood and tissues suggest cancer diagnostic approach
2021/03/11	-	21-9	JH Cha	The human tumor microbiome is composed of tumor type-specific intracellular bacteria

2021
Date	Team	Paper index	Presenter	Paper title
2021/02/22	Single-cell	21-8	IS Choi	Functional CRISPR dissection of gene networks controlling human regulatory T cell identity
2021/02/22	Single-cell	21-7	JH Cha	Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy
2021/02/15	Single-cell	21-6	SB Baek	Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases
2021/02/15	Single-cell	21-5	IS Choi	Trajectory-based differential expression analysis for single-cell sequencing data
2021/02/08	Single-cell	21-4	SB Baek	Genetic determinants of co-accessible chromatin regions in activated T cells across humans
2021/02/08	Single-cell	21-3	JH Cha	Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer
2021/02/01	Single-cell	21-2	JW Cho	Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy
2021/02/01	Single-cell	21-1	JW Cho	Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line

2020-1st semester
Date	Team	Paper index	Presenter	Paper title
2021/02/01	-	20-15	JW Cho	Multi-omic single-cell snapshots reveal multiple independent trajectories to drug tolerance in a melanoma cell line
		20-14	JW Choi	Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment Within Human Melanoma
		20-13	JW Seo	A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
2020/06/09	-	20-12	JY Lee	Single-cell Transcriptional Diversity Is a Hallmark of Developmental Potential
2020/06/09	-	20-11	JH Kim	Landscape and Dynamics of Single Immune Cells in Hepatocellular Carcinoma
2020/06/02	-	20-10	HY Seo	Peripheral T Cell Expansion Predicts Tumour Infiltration and Clinical Response
2020/06/02	-	20-9	KH Hong	Defining T Cell States Associated With Response to Checkpoint Immunotherapy in Melanoma
2020/05/26	-	20-8	JY Seong	Rapid Non-Uniform Adaptation to Conformation-Specific KRAS(G12C) Inhibition
2020/05/26	-	20-7	OY Min	Targeted Therapy Guided by Single-Cell Transcriptomic Analysis in Drug-Induced Hypersensitivity Syndrome: A Case Report
2020/05/19	-	20-6	SN Lee	Distinct Microbial and Immune Niches of the Human Colon
2020/05/19	-	20-5	DJ Park	Massively Parallel Single-Cell Chromatin Landscapes of Human Immune Cell Development and Intratumoral T Cell Exhaustion
2020/05/12	-	20-4	SY Park	Single-cell Gene Expression Reveals a Landscape of Regulatory T Cell Phenotypes Shaped by the TCR
2020/05/12	-	20-3	NY Kim	A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility
2020/04/28	Single-cell	20-2	SB Baek	scAI: An Unsupervised Approach for the Integrative Analysis of Parallel Single-Cell Transcriptomic and Epigenomic Profiles
2020/04/28	Single-cell	20-1	JH Cha	Single-cell Multiomic Analysis Identifies Regulatory Programs in Mixed-Phenotype Acute Leukemia

2019-2nd semester
Date	Team	Paper index	Presenter	Paper title
2019/10/15	Microbiome	19-51	CY Kim	Obese Individuals with and without Type 2 Diabetes Show Different Gut Microbial Functional Capacity and Composition
2019/10/15	Microbiome	19-50	SH Lee	Clustering co-abundant genes identifies components of the gut microbiome that are reproducibly associated with colorectal cancer and inflammatory bowel disease
2019/10/08	Single-cell	19-49	SB Baek	Massively parallel single-cell chromatin landscapes of human immune cell development and intratumoral T cell exhaustion
2019/10/08	Single-cell	19-48	SB Baek	Assessment of computational methods for the analysis of single-cell ATAC-seq data
2019/10/01	Microbiome	19-47	MY Lee	Meta-Analysis Reveals Reproducible Gut Microbiome Alterations in Response to a High-Fat Diet
2019/10/01	Microbiome	19-46	NY Kim	Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes
2019/09/24	Single-cell	19-45	JH Cha	The accessible chromatin landscape of the murine hippocampus at single-cell resolution
2019/09/24	Single-cell	19-44	SB Baek	Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation
2019/09/17	Microbiome	19-43	SH Lee	A sparse covarying unit that describes healthy and impaired human gut microbiota development
2019/09/17	Microbiome	19-42	CY Kim	Large-Scale Analyses of Human Microbiomes Reveal Thousands of Small, Novel Genes
2019/09/10	Single-cell	19-41	KS Kim	Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis
2019/09/10	Single-cell	19-40	IS Choi	Multiplexed droplet single-cell RNA-sequencing using natural genetic variation
2019/09/03	Microbiome	19-39	NY Kim	The Landscape of Genetic Content in the Gut and Oral Human Microbiome
2019/09/03	Microbiome	19-38	CY Kim	Benchmarking Metagenomics Tools for Taxonomic Classification

2019
Date	Paper index	Presenter	Paper title
2019/08/20	19-37	JH Cha	Coexpression uncovers a unified single-cell transcriptomic landscape
2019/08/20	19-36	MY Lee	Single-cell interactomes of the human brain reveal cell-type specific convergence of brain disorders
2019/08/14	19-35	SH Lee	Proportionality: a valid alternative to correlation for relative data
	19-34	SH Lee	propr: An R-package for Identifying Proportionally Abundant Features Using Compositional Data Analysis
	19-33	HJ Han	Robust prediction of response to immune checkpoint blockade therapy in metastatic melanoma
2019/08/13	19-32	KS Kim	A test metric for assessing single-cell RNA-seq batch correction
2019/08/13	19-31	KS Kim	Comprehensive Integration of Single-Cell Data
2019/08/08	19-30	JH Cha	Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma
2019/08/08	19-29	KS Kim	High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy
2019/08/07	19-28	HJ Han	A single-cell reference map for human blood and tissue T cell activation reveals functional states in health and disease
2019/08/07	19-27	IS Choi	Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma
2019/07/30	19-26	IS Choi	High-dimensional single-cell analysis predicts response to anti-PD-1 immunotherapy
2019/07/30	19-25	JW Cho	A Cancer Cell Program Promotes T Cell Exclusion and Resistance to Checkpoint Blockade
2019/07/23	19-24	HJ Han	COMPASS identifies T-cell subsets correlated with clinical outcomes.
2019/07/23	19-23	HJ Han	Sensitive detection of rare disease-associated cell subsets via representation learning
2019/05/30	19-22		Meta-analysis of fecal metagenomes reveals global microbial signatures that are specific for colorectal cancer
	19-21		Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation
	19-20		Microbial network disturbances in relapsing refractory Crohn's disease.
2019/05/23	19-19		New insights from uncultivated genomes of the global human gut microbiome
	19-18		A new genomic blueprint of the human gut microbiota
	19-17		Extensive Unexplored Human Microbiome Diversity Revealed by Over 150,000 Genomes from Metagenomes Spanning Age, Geography, and Lifestyle.
2019/05/16	19-16		Dynamics of metatranscription in the inflammatory bowel disease gut microbiome.
2019/05/16	19-15		Metatranscriptome of human faecal microbial communities in a cohort of adult men.
2019/05/09	19-14		Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT.
2019/05/09	19-13		Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features.
2019/05/02	19-12		Distinct Immune Cell Populations Define Response to Anti-PD-1 Monotherapy and Anti-PD-1/Anti-CTLA-4 Combined Therapy.
2019/05/02	19-11		Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade.
2019/4/11	19-10		Lineage tracking reveals dynamic relationships of T cells in colorectal cancer.
2019/4/11	19-9		Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma.
2019/4/4	19-8		Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis.
2019/4/4	19-7		Global characterization of T cells in non-small-cell lung cancer by single-cell sequencing
2019/3/28	19-6		Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors.
2019/3/28	19-5		Landscape of Infiltrating T Cells in Liver Cancer Revealed by Single-Cell Sequencing.
2019/3/21	19-4		Phenotype molding of stromal cells in the lung tumor microenvironment.
	19-3-1		A single-cell molecular map of mouse gastrulation and early organogenesis
	19-3		The single-cell transcriptional landscape of mammalian organogenesis
2019/3/14	19-2		Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment
2019/3/14	19-1		Single-Cell Transcriptomic Analysis of Primary and Metastatic Tumor Ecosystems in Head and Neck Cancer

2018
Date	Paper index	Presenter	Paper title
2018/06/14	18-12		A Pan-Cancer Analysis of Enhancer Expression in Nearly 9000 Patient Samples.
2018/06/14	18-11		Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation.
2018/06/07	18-10		Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq.
2018/06/07	18-9		Chemoresistance Evolution in Triple-Negative Breast Cancer Delineated by Single-Cell Sequencing.
2018/05/31	18-8		Mapping human pluripotent stem cell differentiation pathways using high throughput single-cell RNA-sequencing.
2018/05/31	18-7		A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex.
2018/05/24	18-6	CY Kim	Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs.
2018/05/24	18-5	HJ Han	FOCS: a novel method for analyzing enhancer and gene activity patterns infers an extensive enhancer-promoter map.
2018/05/17	18-4	KS Kim	A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells.
2018/05/17	18-3	SH Lee	A global transcriptional network connecting noncoding mutations to changes in tumor gene expression.
2018/05/10	18-2	JW Cho	Inferring regulatory element landscapes and transcription factor networks from cancer methylomes.
2018/05/10	18-1	DS Bae	Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma.

2017
Date	Paper index	Presenter	Paper title
2017/06/28	17-36	HJ Han	Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy.
2017/06/28	17-35	JW Cho	Landscape of tumor-infiltrating T cell repertoire of human cancers.
2017/06/14	17-34	JW Cho	The landscape of T cell infiltration in human cancer and its association with antigen presenting gene expression.
2017/06/14	17-33	MY Lee	A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells.
2017/06/07	17-32		Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis.
2017/06/07	17-31	MY Lee	Genomic Correlates of Immune-Cell Infiltrates in Colorectal Carcinoma.
2017/05/31	17-30	DS Bae	Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma.
2017/05/31	17-29	JW Cho	Pan-cancer Immunogenomic Analyses Reveal Genotype-Immunophenotype Relationships and Predictors of Response to Checkpoint Blockade.
2017/05/24	17-28	EB Kim	Systemic Immunity Is Required for Effective Cencer Immunotherapy.
2017/05/24	17-27	CY Kim	Linking the Human Gut Microbiome to Inflammatory Cytokine Production Capacity.
2017/05/17	17-26		Host and Environmental Factors Influencing Individual Human Cytokine Responses.
2017/05/17	17-25		A Functional Genomics Approach to Understand Variation in Cytokine Production in Humans.
2017/04/26	17-24		Pooled CRISPR screening with single-cell transcriptome readout.
2017/04/26	17-23		Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.
2017/04/12	17-22	SH Lee	Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens.
2017/04/12	17-21	CY Kim	Wishbone identifies bifurcating developmental trajectories from single-cell data.
2017/04/05	17-20	KS Kim	Reversed graph embedding resolves complex single-cell developmental trajectories.
2017/04/05	17-19	SH Lee	Single-cell mRNA quantification and differential analysis with Census.
2017/03/29	17-18		Single-Cell Transcriptomic Analysis Defines Heterogeneity and Transcriptional Dynamics in the Adult Neural Stem Cell Lineage.
2017/03/29	17-17	DS Bae	Single-Cell Network Analysis Identifies DDIT3 as a Nodal Lineage Regulator in Hematopoiesis.
2017/03/22	17-16		Single-cell analysis of mixed-lineage states leading to a binary cell fate choice.
2017/03/22	17-15	EB Kim	Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seq.
2017/03/15	17-14		Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq.
2017/03/15	17-13		Single-cell mRNA sequencing identifies subclonal heterogeneity in anti-cancer drug responses of lung adenocarcinoma cells.
2017/02/28	17-12	KS Kim	A Comprehensive Characterization of the Function of LincRNAs in Transcriptional Regulation Through Long-Range Chromatin Interactions.
2017/02/28	17-11	JE Shim	Epigenomic Deconvolution of Breast Tumors Reveals Metabolic Coupling between Constituent Cell Types.
2017/02/21	17-10	EB Kim	Convergence of dispersed regulatory mutations predicts driver genes in prostate cancer.
2017/02/21	17-09	EB Kim	Chromatin structure-based prediction of recurrent noncoding mutations in cancer.
2017/02/07	17-08	DS Bae	Somatic Mutations and Neoepitope Homology in Melanomas Treated with CTLA-4 Blockade.
2017/02/07	17-07	MY Lee	Chemotherapy weakly contributes to predicted neoantigen expression in ovarian cancer.
2017/01/31	17-06	CY Kim	Microbiota Diurnal Rhythmicity Programs Host Transcriptome Oscillations.
2017/01/24	17-05	JW Cho	Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells.
2017/01/17	17-04	HJ Han	Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C
2017/01/17	17-03	EB Kim	CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data.
2017/01/10	17-02	JE Shim	ZIFA: Dimensionality reduction for zero-inflated single-cell gene expression analysis
2017/01/03	17-01	SH Lee	Single-cell messenger RNA sequencing reveals rare intestinal cell types

2016
Date	Paper index	Presenter	Paper title
2016/12/27	2016-31	EB Kim	Decoding the regulatory network of early blood development from single-cell gene expression measurements.
2016/12/6	2016-30	KS Kim	Single-Cell RNA-Seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis.
2016/11/29	2016-29	DS Bae	The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells.
2016/11/22	2016-28	CY Kim	Classification of low quality cells from single-cell RNA-seq data.
2016/11/15	2016-27	MY Lee	Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells.
2016/11/8	2016-26	JW Cho	Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets.
2016/11/1	2016-25	HJ Han	Causal Mechanistic Regulatory Network for Glioblastoma Deciphered Using Systems Genetics Network Analysis.
2016/10/25	2016-24	MY Lee	Comprehensive analyses of tumor immunity: implications for cancer immunotherapy.
2016/10/11	2016-23	JE Shim	Widespread parainflammation in human cancer
2016/9/27	2016-22	ER Kim	Analysis of protein-coding genetic variation in 60,706 humans
2016/9/20	2016-21	SM Yang	Functional characterization of somatic mutations in cancer using network-based inference of protein activity pubmed fulltext
2016/9/13	2016-20	KS Kim	Exploiting single-cell expression to characterize co-expression replicability.
2016/9/6	2016-19	T Lee	Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
2016/8/31	2016-18	DS Bae	A Computational Drug Repositioning Approach for Targeting Oncogenic Transcription Factors
2016/8/16	2016-17	JW Cho	The landscape of accessible chromatin in mammalian preimplantation embryos
2016/8/8	2016-16	EB Kim	Enhancer-promoter interactions are encoded by complex genomic signatures on looping chromatin
2016/8/1	2016-15	MY Lee	Personalized Immunomonitoring Uncovers Molecular Networks that Stratify Lupus Patients
2016/7/25	2016-14	CY Kim	Integration of summary data from GWAS and eQTL studies predicts complex trait gene targets
2016/7/18	2016-13	HJ Han	Identification of transcriptional regulators in the mouse immune system
2016/6/8	2016-12	DS Bae, CY Kim	Mapping the effects of drugs on the immune system
2016/6/8	2016-11	DS Bae, CY Kim	Elucidating compound mechanism of action by network perturbation analysis
2016/6/1	2016-10	MY Lee,SM Cho	Integrative approaches for large-scale transcriptome-wide association studies
2016/6/1	2016-9	MY Lee,SM Cho	Tissue-specific regulatory circuits reveal variable modular perturbations across complex diseases
2016/5/18	2016-8	CY Kim,SJ Kwon	Survey of variation in human transcription factors reveals prevalent DNA binding changes
2016/5/18	2016-7	CY Kim,SJ Kwon	Large-scale identification of sequence variants influencing human transcription factor occupancy in vivo
2016/5/11	2016-6	DS Bae, CY Kim	Predicting Cancer-specific vulnerability via data-driven detection of synthetic lethality
2016/5/11	2016-5	DS Bae, CY Kim	Dynamic regulatory network controlling Th17 cell differentiation
2016/5/4	2016-4	MY Lee,SM Cho	Characterization of the immunophenotypes and antigenomes of colorectal cancers reveals distinct tumor escape mechanisms and novel targets for immunotherapy
2016/5/4	2016-3	MY Lee,SM Cho	Regulators of genetic risk of breast cancer identified by integrative network analysis
2016/4/27	2016-2	CY Kim,SJ Kwon	A predictive computational framework for direct reprogramming between human cell types
2016/4/27	2016-1	CY Kim,SJ Kwon	CellNet: Network biology applied to stem cell engineering

2015
Date	Paper index	Presenter	Paper title
2015/06/11	2015-55		Improved exome prioritization of disease genes through cross-species phenotype comparison.
2015/06/11	2015-54		Phevor combines multiple biomedical ontologies for accurate identification of disease-causing alleles in single individuals and small nuclear families.
2015/06/04	2015-53		eXtasy: variant prioritization by genomic data fusion.
2015/06/04	2015-52		A probabilistic disease-gene finder for personal genomes.
2015/05/28	2015-51		Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types.
2015/05/28	2015-50		GREAT improves functional interpretation of cis-regulatory regions.
2015/05/21	2015-49		Functional annotation of noncoding sequence variants.
2015/05/21	2015-48		FunSeq2: A framework for prioritizing noncoding regulatory variants in cancer.
2015/05/14	2015-47		Selecting causal genes from genome-wide association studies via functionally coherent subnetworks.
2015/05/14	2015-46		Biological interpretation of genome-wide association studies using predicted gene functions.
2015/05/07	2015-45		Human symptoms-disease network.
	2015-44		A nondegenerate code of deleterious variants in Mendelian loci contributes to complex disease risk.
	2015-43		Uncovering disease-disease relationships through the incomplete interactome.
2015/04/30	2015-42		The discovery of integrated gene networks for autism and related disorders.
2015/04/30	2015-41		Integrated systems analysis reveals a molecular network underlying autism spectrum disorders.
2015/04/23	2015-40		Dissecting neural differentiation regulatory networks through epigenetic footprinting.
	2015-39		Cell-of-origin chromatin organization shapes the mutational landscape of cancer.
	2015-38		Integrative analysis of 111 reference human epigenomes.
2015/04/09	2015-37		Genome-wide analysis of local chromatin packing in Arabidopsis thaliana.
2015/04/09	2015-36		A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping.
2015/04/02	2015-35		Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data.
2015/04/02	2015-34		Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells.
2015/03/26	2015-33		Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks.
2015/03/26	2015-32		Characterization of the neural stem cell gene regulatory network identifies OLIG2 as a multifunctional regulator of self-renewal.
2015/03/19	2015-31		Decoding the regulatory network of early blood development from single-cell gene expression measurements.
2015/03/19	2015-30		Computational and analytical challenges in single-cell transcriptomics.
2015/03/12	2015-29		Extensive Strain-Level Copy-Number Variation across Human Gut Microbiome Species.
	2015-28		Richness of human gut microbiome correlates with metabolic markers.
	2015-27		A metagenome-wide association study of gut microbiota in type 2 diabetes.
2015/03/09	2015-26	HJ Han	Practical guidelines for the comprehensive analysis of ChIP-seq data.
	2015-25	T Lee	Patterns of regulatory activity across diverse human cell types predict tissue identity, transcription factor binding, and long-range interactions.
	2015-24	ER Kim	Rapid neurogenesis through transcriptional activation in human stem cells.
2015/03/02	2015-23	DS Bae	Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation.
	2015-22	CY Kim	Integrating multiple genomic data to predict disease-causing nonsynonymous single nucleotide variants in exome sequencing studies.
	2015-21	ER Kim	The Genotype-Tissue Expression (GTEx) project.
2015/02/24	2015-20	ER Kim	Mouse regulatory DNA landscapes reveal global principles of cis-regulatory evolution.
	2015-19	KS Kim	Principles of regulatory information conservation between mouse and human.
	2015-18	BH Kang	Conservation of trans-acting circuitry during mammalian regulatory evolution.
2015/02/16	2015-17	T Lee	Genetic and epigenetic fine mapping of causal autoimmune disease variants.
	2015-16	CY Kim	A general framework for estimating the relative pathogenicity of human genetic variants.
	2015-15	CY Kim	A probabilistic model to predict clinical phenotypic traits from genome sequencing.
2015/02/02	2015-14	BH Kang	Relating the metatranscriptome and metagenome of the human gut.
	2015-13	BH Kang	Alterations of the human gut microbiome in liver cirrhosis.
	2015-12	CY Kim	An integrated catalog of reference genes in the human gut microbiome.
	2015-11	CY Kim	Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes.
2015/01/26	2015-10	HH Kim	Computational meta'omics for microbial community studies.
	2015-09	HH Kim	Functional profiling of the gut microbiome in disease-associated inflammation.
	2015-08	BH Kang	Biodiversity and functional genomics in the human microbiome.
	2015-07	BH Kang	Chapter 12: Human Microbiome Analysis.
	2015-06	BH Kang	Conducting a Microbiome Study.
2015/01/12	2015-05	KS Kim	Small RNA changes en route to distinct cellular states of induced pluripotency.
	2015-04	DS Bae	Genome-wide characterization of the routes to pluripotency.
	2015-03	DS Bae	Divergent reprogramming routes lead to alternative stem-cell states.
2015/01/05	2015-02	HJ Han	Global view of enhancer-promoter interactome in human cells.
2015/01/05	2015-01	HJ Han	Combining Hi-C data with phylogenetic correlation to predict the target genes of distal regulatory elements in human genome.

2014
Date	Paper index	Presenter	Paper title
2014/12/23	2014-41	CY Kim	Super-enhancers in the control of cell identity and disease.
2014/12/23	2014-40	CY Kim	Master transcription factors and mediator establish super-enhancers at key cell identity genes.
2014/12/09	2014-39	HH Kim	Unraveling the biology of a fungal meningitis pathogen using chemical genetics.
	2014-38	JE Shim	A proteome-scale map of the human interactome network.
	2014-37	JE Shim	The role of the interactome in the maintenance of deleterious variability in human populations.
	2014-36	HS Shim	Integrative annotation of variants from 1092 humans: application to cancer genomics.
2014/12/02	2014-35	HJ Han	Mapping functional transcription factor networks from gene expression data.
2014/12/02	2014-34	KS Kim	In pursuit of design principles of regulatory sequences.
2014/11/25	2014-33	KS Kim	Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease.
2014/11/25	2014-32	HJ Han	Developmental fate and cellular maturity encoded in human regulatory DNA landscapes.
2014/11/18	2014-31	SM Yang	The 'dnet' approach promotes emerging research on cancer patient survival.
2014/11/18	2014-30	HJ Han	Determination and inference of eukaryotic transcription factor sequence specificity.
2014/11/11	2014-29	DS Bae	Transcription factors interfering with dedifferentiation induce cell type-specific transcriptional profiles.
	2014-28	HH Kim	Dissecting engineered cell types and enhancing cell fate conversion via CellNet.
	2014-27	HH Kim	CellNet: network biology applied to stem cell engineering.
2014/11/04	2014-26	HS Shim	Predicting Cancer-Specific Vulnerability via Data-Driven Detection of Synthetic Lethality.
2014/11/04	2014-25	JH Shin	Phen-Gen: combining phenotype and genotype to analyze rare disorders.
2014/10/28	2014-24	HJ Han	A community effort to assess and improve drug sensitivity prediction algorithms.
2014/10/28	2014-23	HS Shim	Multi-tiered genomic analysis of head and neck cancer ties TP53 mutation to 3p loss.
2014/09/30	2014-22	JE Shim	Network-based stratification of tumor mutations.
2014/09/30	2014-21	KS Kim	Synonymous mutations frequently act as driver mutations in human cancers.
2014/09/23	2014-20	CY Kim	VarWalker: Personalized Mutation Network Analysis of Putative Cancer Genes from Next-Generation Sequencing Data.
2014/09/23	2014-19	HJ Han	DriverNet: uncovering the impact of somatic driver mutations on transcriptional networks in cancer.
2014/09/16	2014-18	JH Shin	Integrated analysis of recurrent properties of cancer genes to identify novel drivers.
2014/09/16	2014-17	AR Cho	Improving the prediction of the functional impact of cancer mutations by baseline tolerance transformation.
2014/09/02	2014-16	JE Shim	A network module-based method for identifying cancer prognostic signatures.
2014/09/02	2014-15	AR Cho	Realizing the promise of cancer predisposition genes.
2014/08/19	2014-14	JE Shim	Assessing the clinical utility of cancer genomic and proteomic data across tumor types.
2014/08/19	2014-13	HS Shim	Mutational landscape and significance across 12 major cancer types.
2014/08/12	2014-12	HS Shim	Signatures of mutational processes in human cancer.
2014/08/12	2014-11	HJ Kim	Discovery and saturation analysis of cancer genes across 21 tumour types.
2014/08/05	2014-10	CY Kim	Comprehensive identification of mutational cancer driver genes across 12 tumor types.
2014/08/05	2014-9	JE Shim	IntOGen-mutations identifies cancer drivers across tumor types.
2014/07/29	2014-8	CY Kim	Computational approaches to identify functional genetic variants in cancer genomes.
	2014-7	AR Cho	Mutational heterogeneity in cancer and the search for new cancer-associated genes.
	2014-6	AR Cho	Cancer genomes: discerning drivers from passengers
2014/07/22	2014-5	AR Cho	The Cancer Genome Atlas Pan-Cancer analysis project.
	2014-4	AR Cho	Cancer genome landscapes.
	2014-3	AR Cho	Distinguishing driver and passenger mutations in an evolutionary history categorized by interference.
2014/07/15	2014-2	HJ Han	A promoter-level mammalian expression atlas.
2014/07/15	2014-1	HJ Han	An atlas of active enhancers across human cell types and tissues.

2013
Date	Paper index	Presenter	Paper title
2013/06/26	2013-31	HJ Han	Integration of Hi-C and ChIP-seq data reveals distinct types of chromatin linkages
2013/06/26	2013-30	YH Ko	Deciphering molecular circuits from genetic variation underlying transcriptional responsiveness to stimuli
2013/06/04	2013-29	KS Kim	Mapping the Human miRNA Interactome by CLASH Reveals Frequent Noncanonical Binding
2013/06/04	2013-28	ER Kim	Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples
2013/05/28	2013-27	YH Ko	Discovering statistically significant pathways in expression profiling studies
2013/05/28	2013-26	JE Shim	Prediction and Validation of Gene-Disease Associations Using Methods Inspired by Social Network Analyses
2013/05/21	2013-25	HJ Han	Dynamic regulatory network controlling TH17 cell differentiation
2013/05/21	2013-24	T Lee	Deciphering and Prediction of Transcriptome Dynamics under Fluctuating Field Conditions
2013/05/14	2013-23	JE Shim	Integrative eQTL-Based Analyses Reveal the Biology of Breast Cancer Risk Loci
2013/05/14	2013-22	HJ Kim	Chromatin marks identify critical cell types for fine mapping complex trait variants
2013/05/07	2013-21	ER Kim	Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues
2013/05/07	2013-20	HS Shim	Human Disease-Associated Genetic Variation Impacts Large Intergenic Non-Coding RNA Expression
2013/04/09	2013-19	HJ Kim	Annotation of functional variation in personal genomes using RegulomeDB
2013/04/02	2013-18	HJ Kim	The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression
2013/03/12	2013-17	ER Kim	Global Mapping of Cell Type–Specific Open Chromatin by FAIRE-seq Reveals the Regulatory Role of the NFI Family in Adipocyte Differentiation
2013/03/05	2013-16	ER Kim	ChIP–seq: advantages and challenges of a maturing technology
2013/02/21	2013-15	KS Kim	Novel Modeling of Combinatorial miRNA Targeting Identifies SNP with Potential Role in Bone Density
	2013-14	KS Kim	A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells
	2013-13	HJ Han	Differential DNase I hypersensitivity reveals factor-dependent chromatin dynamics.
2013/02/15	2013-12	HJ Han	Chromatin accessibility pre-determines glucocorticoid receptor binding patterns
	2013-11	JE Shim, CY Kim	Interpreting noncoding genetic variation in complex traits and human disease
	2013-10	HJ Han, JH Kim	Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data
2013/02/08	2013-09	HJ Kim	Widespread Site-Dependent Buffering of Human Regulatory Polymorphism
	2013-08	JE Shim, CY Kim	Linking disease associations with regulatory information in the human genome
	2013-07	HJ Han, JH Kim	Understanding transcriptional regulation by integrative analysis of transcription factor binding data
2013/01/25	2013-06	HJ Han, JH Kim	The long-range interaction landscape of gene promoters
	2013-05	ER Kim, HS Shim	Landscape of transcription in human cells
	2013-04	HJ Han, JH Kim	Architecture of the human regulatory network derived from ENCODE data
2013/01/18	2013-03	KS Kim, TH Kim	An expansive human regulatory lexicon encoded in transcription factor footprints
2013/01/18	2013-02	HJ Han, JH Kim	The accessible chromatin landscape of the human genome
2013/01/11	2013-01	JE Shim, CY Kim	An integrated encyclopedia of DNA elements in the human genome

2012

Date	Paper index	Paper title
2013/01/11	2012-81	(TH Kim) MuSiC: identifying mutational significance in cancer genomes.
2012/12/04	2012-80	(CY KIM) Human genomic disease variants: A neutral evolutionary explanation
2012/11/20	2012-79	(HS Shim) Circuitry and Dynamics of Human Transcription Factor Regulatory Networks
2012/11/20	2012-78	(HJ Kim) Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins
2012/11/06	2012-77	(HJ Han) Systematic Localization of Common Disease-Associated Variation in Regulatory DNA
2012/11/06	2012-76	(KS Kim) A public resource facilitating clinical use of genomes
2012/07/19	2012-75	(HJ Han & YH Ko) Predictive regulatory models in Drosophila melanogaster by integrative inference of transcriptional networks
	2012-74	(JE Shim) An Abundance of Rare Functional Variants in 202 Drug Target Genes Sequenced in 14,002 People
	2012-73	(JE Shim) Evolution and Functional Impact of Rare Coding Variation from Deep Sequencing of Human Exomes
	2012-72	(SH Hwang) Network-based classification of breast cancer metastasis
	2012-71	(T Lee&CY Kim)Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants
	2012-70	(ER Kim&TH Kim)The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
2012/07/16	2012-69	(ER Kim&TH Kim)A framework for variation discovery and genotyping using next-generation DNA sequencing data
	2012-66	(ER Kim&TH Kim)The Sequence Alignment/Map format and SAMtools
	2012-65	(ER Kim&TH Kim)The Variant Call Format and VCFtools
	2012-64	(YH Go&HJ Han)The Impact of the Gut Microbiota on Human Health: An Integrative View
	2012-63	(T Lee&CY Kim)Host-Gut Microbiota Metabolic Interactions
	2012-62	(AR Cho,JH Ju)Interactions Between the Microbiota and the Immune System
	2012-61	(SH Hwang&HJ Cho)The Application of Ecological Theory Toward an Understanding of the Human Microbiome
	2012-60	(SH Hwang&HJ Cho)Microbiota-Targeted Therapies: An Ecological Perspective
2012/07/13	2012-59	(JH Shin&HJ Kim)Metabolic Reconstruction for Metagenomic Data and Its Application to the Human Microbiome
	2012-58	(JH Shin&HJ Kim)A framework for human microbiome research
	2012-57	(JH Shin&HJ Kim)Structure, function and diversity of the healthy human microbiome
2012/07/12	2012-56	(AR Cho&JH Ju)COLT-Cancer: functional genetic screening resource for essential genes in human cancer cell lines
	2012-55	(YH Go&HJ Han)Google Goes Cancer: Improving Outcome Prediction for Cancer Patients by Network-Based Ranking of Marker Genes
	2012-54	(YH Go&HJ Han)A pharmacogenomic method for individualized prediction of drug sensitivity
	2012-53	(JH Soh)The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
2012/07/09	2012-52	(ER Kim&TH Kim)The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
	2012-51	(ER Kim&TH Kim)Systematic identification of genomic markers of drug sensitivity in cancer cells
	2012-50	(ER Kim&TH Kim)Subtype and pathway specific responses to anticancer compounds in breast cancer
	2012-49	(JE Shim&KS Kim)De novo mutations revealed by whole-exome sequencing are strongly associated with autism
	2012-48	(JE Shim&KS Kim)Patterns and rates of exonic de novo mutations in autism spectrum disorders
	2012-47	(JE Shim&KS Kim)Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations
2012/07/06	2012-46	(T Lee&CY Kim)Integrating Rare-Variant Testing, Function Prediction, and Gene Network in Composite Resequencing-Based Genome-Wide Association Studies (CR-GWAS)
	2012-45	(T Lee&CY Kim)Type 2 Diabetes Risk Alleles Demonstrate Extreme Directional Differentiation among Human Populations, Compared to Other Diseases
	2012-44	(AR Cho&JH Ju)Predicting mutation outcome from early stochastic variation in genetic interaction partners
	2012-43	(AR Cho&JH Ju)Fitness Trade-Offs and Environmentally Induced Mutation Buffering in Isogenic C. elegans
	2012-42	(JE Shim&KS Kim)Identification of microRNA-regulated gene networks by expression analysis of target genes
	2012-41	(JE Shim&KS Kim)Exome sequencing and the genetic basis of complex traits
2012/07/02	2012-40	(JH Soh)Functional Repurposing Revealed by Comparing S. pombe and S. cerevisiae Genetic Interactions
	2012-39	(ER Kim&TH Kim)De novo discovery of mutated driver pathways in cancer
	2012-38	(YH Go&HJ Han)A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas
	2012-37	(SH Hwang&HJ Cho)PREDICT: a method for inferring novel drug indications with application to personalized medicine
	2012-36	(SH Hwang&HJ Cho)Synergistic response to oncogenic mutations defines gene class critical to cancer phenotype
	2012-35	(JH Shin&HJ Kim)Detecting Novel Associations in Large Data Sets
2012/03/05	2012-34	(8,HH Kim)Mapping and quantifying mammalian transcriptomes by RNA-Seq.
	2012-33	(11,Go&Ju)Differential expression analysis for sequence count data
	2012-32	(12,Go&Ju)edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
2012/02/27 2012/02/28	2012-31	(1,JW Song)RNA-Seq: a revolutionary tool for transcriptomics
	2012-30	(2,JW Song)Computational methods for transcriptome annotation and quantification using RNA-seq
	2012-29	(3,HJ Han)From RNA-seq reads to differential expression results
	2012-28	(4,AR Cho)Comprehensive comparative analysis of strand-specific RNA sequencing methods
	2012-27	(5,T Lee)A Low-Cost Library Construction Protocol and Data Analysis Pipeline for Illumina-Based Strand-Specific Multiplex RNA-Seq
	2012-26	(6,So&Shin)Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation
	2012-25	(7,So&Shin)TopHat: discovering splice junctions with RNA-Seq
2012/02/06	2012-24	mirConnX: condition-specific mRNA-microRNA network integrator
	2012-23	Construction and Analysis of an Integrated Regulatory Network Derived from High-Throughput Sequencing Data
	2012-22	A Densely Interconnected Genome-Wide Network of MicroRNAs and Oncogenic Pathways Revealed Using Gene Expression Signatures
	2012-21	Reprogramming of miRNA networks in cancer and leukemia
	2012-20	An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma
2012/01/30	2012-19	Principles and Strategies for Developing Network Models in Cancer
	2012-18	Reverse engineering of regulatory networks in human B cells
	2012-17	Variations in DNA elucidate molecular networks that cause disease
	2012-16	Harnessing gene expression to identify the genetic basis of drug resistance
	2012-15	An Integrated Approach to Uncover Drivers of Cancer
2012/01/09	2012-14	Genetic variation in an individual human exome.
	2012-13	Predicting phenotypic variation in yeast from individual genome sequences.
	2012-12	Clinical assessment incorporating a personal genome.
2012/01/09 2012/01/16	2012-11	Human allelic variation: perspective from protein function, structure, and evolution.
	2012-10	Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm.
	2012-09	Prediction of deleterious human alleles.
	2012-08	Human non-synonymous SNPs: server and survey.
	2012-07	A method and server for predicting damaging missense mutations.
	2012-06	SNAP: predict effect of non-synonymous polymorphisms on function
2012/01/09 2012/01/16	2012-05	Computational and statistical approaches to analyzing variants identified by exome sequencing.
	2012-04	Shifting paradigm of association studies: value of rare single-nucleotide polymorphisms.
	2012-03	Targeted capture and massively parallel sequencing of 12 human exomes.
2012/01/09 2012/01/16	2012-02	The distribution of fitness effects of new mutations.
2012/01/09 2012/01/16	2012-01	Most Rare Missense Alleles Are Deleterious in Humans: Implications for Complex Disease and Association Studies

2011

Date	Paper_index	Paper_title
2011/11/28	2011-49	(Shin)Data-Driven Methods to Discover Molecular Determinants of Serious Adverse Drug Events
	2011-48	(Shin)Network pharmacology: the next paradigm in drug discovery
	2011-47	(Oh)Systematic exploration of synergistic drug pairs
	2011-46	(Shim)Chemogenomic profiling predicts antifungal synergies
	2011-45	(Beck)A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery
	2011-44	(Hwang)Analysis of drug-induced effect patterns to link structure and side effects of medicines
2011/11/14	2011-43	Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets
	2011-42	Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole
	2011-41	Analysis of multiple compound–protein interactions reveals novel bioactive molecules
2011/11/07	2011-40	Drug—target network
	2011-39	A side effect resource to capture phenotypic effects of drugs
	2011-38	Quantitative systems-level determinants of human genes targeted by successful drugs
	2011-37	Drug Target Identification Using Side-Effect Similarity
2011/11/07	2011-36	Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data
	2011-35	Exploiting drug–disease relationships for computational drug repositioning
	2011-34	Drug Discovery in a Multidimensional World: Systems, Patterns, and Networks
2011/10/05	2011-33	Analysis of membrane proteins in metagenomics: Networks of correlated environmental features and protein families
	2011-32	Quantifying environmental adaptation of metabolic pathways in metagenomics
	2011-31	Quantitative assessment of protein function prediction from metagenomics shotgun sequences
2011/10/04	2011-30	A human gut microbial gene catalogue established by metagenomic sequencing
	2011-29	Molecular eco-systems biology: towards an understanding of community function
	2011-28	Microbial community profiling for human microbiome projects: Tools, techniques, and challenges
	2011-27	Unravelling the effects of the environment and host genotype on the gut microbiome
2011/09/19	2011-26	independently evolved virulence effectors converge onto hubs in a plant immune system Network
2011/09/19	2011-25	Evidence for network evolution in an arabidopsis interactome Map
2011/09/05	2011-24	Exome Sequencing of Ion Channel Genes Reveals Complex Profiles Confounding Personal Risk Assessment in Epilepsy
2011/09/05	2011-23	Pluripotency factors in Embryonic stem cells Regulate Differentiation into Germ Layers
2011/09/22	2011-22	Integrated Genome-scale predition of Detrimental Mutations in Transcription Networks
2011/09/22	2011-21	From expression QTLs to personalized transcriptomics
2011/06/20	2011-20	a user's guide to the encyclopedia of DNA elements(ENCODE)
2011/03/30	2011-19	enterotypes of the human gut microbiome
2011/03/30	2011-18	toward molecular trait-based ecology, through intergration of biogeochemical, geographical and metagenomic data
2011/03/16	2011-17	variable pathogenicity determines individual lifespan in caenorhabditis elegans
2011/03/16	2011-16	a high-resolution c.elegans essential gene network based on phenotypic profiling of a complex tissue
2011/04/25	2011-15	Hallmarks of Cancer : The next generation
	2011-14	Mapping Cancer Origins
	2011-13	Genetic Interactions in Cancer Progression and Treatment
2011/04/11	2011-12	Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology
2011/04/11	2011-11	*Changed!* Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions
2011/03/28	2011-10	profiling translatomes of discrete cell populations resolves altered cellular priorities during hypoxia in Arabidopsis
2011/03/28	2011-09	cell-type specific analysis of translating RNAs in developing flowers reveals new levels of control
2011/03/14	2011-08	phenotypic landscape of a bacterial cell
2011/03/14	2011-07	cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action
2011/02/28	2011-06	genomic patterns of pleiotropy and the evolution of complexity
2011/02/28	2011-05	simultaneous genome-wide inference of physical, genetic, regulatory, and functional pathway
2011/02/21	2011-04	dynamic interaction networks in a hierarchically organized tissue
2011/02/14	2011-03	rewiring of genetic networks in response to DNA damage
2011/01/31	2011-02	Applying mass spectrometry-based proteomics to genetics, genomics and network biology
2011/01/31	2011-01	Data analysis and bioinformatics tools for tandem mass spectrometry in proteomics

2010

Date	Paper_index	Paper_title
2010/12/27	2010-29	Functional_roles_fornoise_in_genetic_circuits
2010/12/27	2010-28	Estimation_of_effect_size_distribution_from_genome-wide_association_studies_and_implications_for_future_discoveries
2010/11/15	2010-27	Liver_and_Adipose_Expression_associated_SNPs_are_enriched_for_association_to_type_2_diabetes
2010/11/15	2010-26	It's_the_machine_that_matters:_predicting_gene_function_and_phenotype_from_protein_networks
2010/11/01	2010-25	A_genome-wide_map_of_human_genetic_interactions_inferred_from_radiation_hybrid_genotypes
2010/11/01	2010-24	A_Genome-Wide_Gene_Function_Prediction_Resource_for_Drosophila_melanogaster
2010/10/11	2010-23	Dissecting_spatio-temporal_protein_networks_driving_human_heart_development_and_related_disorders
2010/09/13	2010-22	Transposable_elements_have_rewired_the_core_regulatory_network_of_human_embryonic_stem_cells
2010/09/13	2010-21	Limits_of_sequence_and_functional_conservation
2010/05/26	2010-20	network_based_elucidation_of_human_disease_similarities_reveals_common_functional_modules_enriched_for_pluripotent_drug_targets.pdf
2010/05/19	2010-19	interpreting_metabolomic_profiles_using_unbiased_pathway_models.pdf
2010/04/21	2010-18	identification_of_networks_of_co_occurring_tumor_related_dna_copy_number_changes_using_a_genome_wide_scoringapproach.pdf
2010/04/14	2010-17	an_atlas_of_combinatorial_transcriptional_regulation_in_mouse_and_man
2010/04/07	2010-16	systematic_discovery_of_nonobvious_human_disease_models_through_orthologous_phenotypes
2010/04/07	2010-15	genome_side_association_study_of_107_phenotypes_in_Arabidopsis_thaliana_inbred_lines
2010/03/31	2010-14	toward_stem_cell_systems_biology_from_molecules_to_networks_and_landscapes.pdf
2010/03/31	2010-13	systems_biology_of_stem_cell_fate_and_cellular_reprogramming
2010/03/24	2010-12	dynamic_modularity_in_protein_interaction_networks_predicts_breast_cancer_outcome
2010/01/18	2010-11	JournalClub_100118_a_tutorial_on_statistical_methods_for_population_association_studies
2010/01/16	2010-10	systems-level_dinamic_analyses_of_fate_change_in_murine_embryonic_stem_cells
2010/01/15	2010-09	distinguishing_direct_versus_indirect_transcription_factor-DNA-interactions
2010/01/14	2010-08	chemogenomic_profiling_predicts_antifungal_synergies
2010/01/13	2010-07	edgetic_perturbation_models_of_human_inherited_disorders
2010/01/12	2010-06	analysis_of_cell_fate_from_single-cell_gene_expression_profiles_in_C.elegans
2010/01/11	2010-05	predicting_new_molecular_targets_for_known_drugs.pdf Reference:SEA(Similarity Ensemble Approach)
2010/01/09	2010-04	harnessing_gene_expression_to_identify_the_genetic_basis_of_drug_resistance
2010/01/08	2010-03	an_integrative_approach_to_reveal_driver_gene_fusions_from_paired_end_sequencing_data_in_cancer
2010/01/07	2010-02	a_phenotypic_profile_of_the_candida_albicans_regulatory_network
2010/01/06	2010-01	a_global_view_of_protein_expression_in_human_cells_tissues_and_organs

@@ Line 48: / Line 48: @@
 |style="padding:.4em;"|EJ Sung
 |style="padding:.4em;text-align:left"|
-[https://doi.org/10.1016/j.patter.2022.100443 EMBEDR: Distinguishing signal from noise in single-cell omics data]
+[https://www.biorxiv.org/content/10.1101/2021.06.07.447430v2 Metacells untangle large and complex single-cell transcriptome networks]
+[https://genomebiology.biomedcentral.com/articles/10.1186/s13059-019-1812-2 MetaCell: analysis of single-cell RNA-seq data using K-nn graph partitions]
+[https://genomebiology.biomedcentral.com/articles/10.1186/s13059-022-02667-1 Metacell‑2: a divide‑and‑conquer metacell algorithm for scalable scRNA‑seq analysis]
 |-
 |style="padding:.4em;" rowspan=1|2022/06/23

Difference between revisions of "Journal Club"

Revision as of 20:52, 1 July 2022

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