Journal Club
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|rowspan = "6" |
|rowspan = "6" |November 28 Mon, 2011
|rowspan = "6" | TY Oh,
SH Hwang,
JE Shim,
S Beck,
JH Shin
|(Shin)Data-Driven Methods to Discover Molecular Determinants of Serious Adverse Drug Events
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|(Shin)Network pharmacology: the next paradigm in drug discovery
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|(Oh)Systematic exploration of synergistic drug pairs
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|(Shim)Chemogenomic profiling predicts antifungal synergies
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|(Beck)A strategy for predicting the chemosensitivity of human cancers and its application to drug discovery
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|(Hwang)Analysis of drug-induced effect patterns to link structure and side effects of medicines
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|rowspan = "3" |
|rowspan = "3" |November 14 Mon, 2011
|rowspan = "3" | HH Kim & AR Cho
|Network-Based Elucidation of Human Disease Similarities Reveals Common Functional Modules Enriched for Pluripotent Drug Targets
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|Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole
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|Analysis of multiple compound–protein interactions reveals novel bioactive molecules
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|rowspan = "4" |
|rowspan = "4" |November 7 Mon, 2011
|rowspan = "4" | YH Ko
|Drug—target network
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|A side effect resource to capture phenotypic effects of drugs
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|Quantitative systems-level determinants of human genes targeted by successful drugs
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|Drug Target Identification Using Side-Effect Similarity
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|rowspan = "3" |
|rowspan = "3" |November 7 Mon, 2011
|rowspan = "3" | JW Song
|Discovery and Preclinical Validation of Drug Indications Using Compendia of Public Gene Expression Data
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|Exploiting drug–disease relationships for computational drug repositioning
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|Drug Discovery in a Multidimensional World: Systems, Patterns, and Networks
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|rowspan = "3" |
|rowspan = "3" |October 5 Mon, 2011
|rowspan = "3" | HH Kim
|Analysis of membrane proteins in metagenomics: Networks of correlated environmental features and protein families
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|Quantifying environmental adaptation of metabolic pathways in metagenomics
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|Quantitative assessment of protein function prediction from metagenomics shotgun sequences
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|rowspan = "4" |
|rowspan = "4" |October 4 Mon, 2011
|rowspan = "4" | S Beck
|A human gut microbial gene catalogue established by metagenomic sequencing
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|Molecular eco-systems biology: towards an understanding of community function
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|Microbial community profiling for human microbiome projects: Tools, techniques, and challenges
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|Unravelling the effects of the environment and host genotype on the gut microbiome
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|rowspan = "2" |
|rowspan = "2" |September 19 Mon, 2011
|rowspan = "2" | TY Oh
|independently evolved virulence effectors converge onto hubs in a plant immune system Network
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|Evidence for network evolution in an arabidopsis interactome Map
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|rowspan = "2" |
|rowspan = "2" |September 5 Mon, 2011
|SG Ji
|Exome Sequencing of Ion Channel Genes Reveals Complex Profiles Confounding Personal Risk Assessment in Epilepsy
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|SH Hwang
|Pluripotency factors in Embryonic stem cells Regulate Differentiation into Germ Layers
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|rowspan = "2" |
|rowspan = "2" | August 22 Mon, 2011
|ER Kim
|Integrated Genome-scale predition of Detrimental Mutations in Transcription Networks
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|T Lee
|From expression QTLs to personalized transcriptomics
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|June 20 Mon, 2011
|JH Shin
|a user's guide to the encyclopedia of DNA elements(ENCODE)
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|rowspan = "2" |
|rowspan = "2" | May 30 Mon, 2011
|rowspan = "2" | HH Kim
|enterotypes of the human gut microbiome
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|toward molecular trait-based ecology, through intergration of biogeochemical, geographical and metagenomic data
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|rowspan = "2" | |rowspan = "2" | May 16 Mon, 2011 |rowspan = "2" | AR Cho |variable pathogenicity determines individual lifespan in caenorhabditis elegans |- |a high-resolution c.elegans essential gene network based on phenotypic profiling of a complex tissue |- |rowspan = "3" | |rowspan = "3" |April 25 Mon, 2011 |rowspan = "3" |S Beck |Hallmarks of Cancer : The next generation |- |Mapping Cancer Origins |- |Genetic Interactions in Cancer Progression and Treatment |- |rowspan = "2" | |rowspan = "2" |April 11 Mon, 2011 |JE Shim |Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology |- |T Lee |***Changed!*** Identifying relationships among genomic disease regions: predicting genes at pathogenic SNP associations and rare deletions |- |rowspan = "2"| |rowspan = "2"|March 28 Mon, 2011 |rowspan = "2"|TY Oh |profiling translatomes of discrete cell populations resolves altered cellular priorities during hypoxia in Arabidopsis |- |cell-type specific analysis of translating RNAs in developing flowers reveals new levels of control |- |rowspan = "2"| |rowspan = "2"|March 14 Mon, 2011 |rowspan = "2"|JW Song |phenotypic landscape of a bacterial cell |- |cross-species chemogenomic profiling reveals evolutionarily conserved drug mode of action |-
|rowspan = "2"| |rowspan = "2"|February 28 Mon, 2011 |KS Kim |genomic patterns of pleiotropy and the evolution of complexity |- |HJ Han |simultaneous genome-wide inference of physical, genetic, regulatory, and functional pathway |- | |February 21 Mon, 2011 |MH Lee |dynamic interaction networks in a hierarchically organized tissue |- | |February 14 Mon, 2011 |AR Cho |rewiring of genetic networks in response to DNA damage |- |rowspan = "2"| |rowspan = "2"|January 31 Mon, 2011 |rowspan = "2"|JW Song |Applying mass spectrometry-based proteomics to genetics, genomics and network biology |- |Data analysis and bioinformatics tools for tandem mass spectrometry in proteomics |- |rowspan = "2"| |rowspan = "2" | December 27 Mon, 2010 |ER Kim |Functional_roles_fornoise_in_genetic_circuits |- |T Lee |Estimation_of_effect_size_distribution_from_genome-wide_association_studies_and_implications_for_future_discoveries |- |rowspan = "2"| |rowspan = "2"|November 15 Mon, 2010 |AR Cho |Liver_and_Adipose_Expression_associated_SNPs_are_enriched_for_association_to_type_2_diabetes |- |SG Ji |It's_the_machine_that_matters:_predicting_gene_function_and_phenotype_from_protein_networks |- |rowspan = "2"| |rowspan = "2"|November 1 Mon, 2010 |HH Kim |A_genome-wide_map_of_human_genetic_interactions_inferred_from_radiation_hybrid_genotypes |- |JH Shin |A_Genome-Wide_Gene_Function_Prediction_Resource_for_Drosophila_melanogaster |- | |October 11 Mon, 2010 |JE Shim |Dissecting_spatio-temporal_protein_networks_driving_human_heart_development_and_related_disorders |- | |September 13 Mon, 2010 |SH Hwang |Transposable_elements_have_rewired_the_core_regulatory_network_of_human_embryonic_stem_cells Limits_of_sequence_and_functional_conservation |- | |May 26 Wed, 2010 |AR Cho |network_based_elucidation_of_human_disease_similarities_reveals_common_functional_modules_enriched_for_pluripotent_drug_targets.pdf |- | |May 19 Wed, 2010 |SG Ji |interpreting_metabolomic_profiles_using_unbiased_pathway_models.pdf |- | |April 21 Wed, 2010 |JH Shin |identification_of_networks_of_co_occurring_tumor_related_dna_copy_number_changes_using_a_genome_wide_scoringapproach.pdf |- | |April 14 Wed, 2010 |TY Oh |an_atlas_of_combinatorial_transcriptional_regulation_in_mouse_and_man |- |rowspan = "2" | |rowspan = "2" |April 7 Wed, 2010 |HHkim | systematic_discovery_of_nonobvious_human_disease_models_through_orthologous_phenotypes |- |T Lee | genome_side_association_study_of_107_phenotypes_in_Arabidopsis_thaliana_inbred_lines |- | |Mar 31 Wed, 2010 |JE Shim |toward_stem_cell_systems_biology_from_molecules_to_networks_and_landscapes.pdf systems_biology_of_stem_cell_fate_and_cellular_reprogramming |- | |Mar 24 Wed, 2010 |SH Hwang |dynamic_modularity_in_protein_interaction_networks_predicts_breast_cancer_outcome |- | |Jan 18 Mon, 2010 |TY Oh(T Lee) |JournalClub_100118_a_tutorial_on_statistical_methods_for_population_association_studies |- | |Jan 16 Sat, 2010 |JE Shim(MH Lee) |systems-level_dinamic_analyses_of_fate_change_in_murine_embryonic_stem_cells |- | |Jan 15 Fri, 2010 |SG Ji |distinguishing_direct_versus_indirect_transcription_factor-DNA-interactions |- | |Jan 14 Thu, 2010 |HH kim |chemogenomic_profiling_predicts_antifungal_synergies |- | |Jan 13 Wed, 2010 |JH Shin(ER Kim) |edgetic_perturbation_models_of_human_inherited_disorders |- | |Jan 12 Tue, 2010 |TY Oh(T Lee) |analysis_of_cell_fate_from_single-cell_gene_expression_profiles_in_C.elegans |- | |Jan 11 Mon, 2010 |JE Shim(MH Lee) |predicting_new_molecular_targets_for_known_drugs.pdf Reference:SEA(Similarity Ensemble Approach) |- | |Jan 09 Sat, 2010 |SG Ji |harnessing_gene_expression_to_identify_the_genetic_basis_of_drug_resistance |- | |Jan 08 Fri, 2010 |AR Cho |an_integrative_approach_to_reveal_driver_gene_fusions_from_paired_end_sequencing_data_in_cancer |- | |Jan 07 Thu, 2010 |HH Kim |a_phenotypic_profile_of_the_candida_albicans_regulatory_network |- | |Jan 06 Wed, 2010 |JH Shin(ER Kim) |a_global_view_of_protein_expression_in_human_cells_tissues_and_organs |}
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