Software

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CODE and DATABASE in Central Repositories

Microbiome Research

150px HRGM: A Human Reference Gut Microbiome comprising 232,098 genomes for 5414 prokaryotic species and 103 million unique proteins


150px HROM: A Human Reference Oral Microbiome comprising 72,641 genomes for 3,426 prokaryotic species and 8.49 million unique proteins

150px MRGM: A Mouse Reference Gut Microbiome comprising 46,267 genomes for 1,689 bacterial species and 15.2 million proteins

150px MRGV: A Mouse Reference Gut Virome comprising 109,778 genomes for 28,824 species-level vOTUs and 1.3 million unique proteins

Single-cell Biology

150px scHumanNet: Cell-type-specific functional gene networks using single-cell RNA-sequencing data

150px VirtualCytometry: A webserver for the study of immune cell differentiation using single-cell RNA sequencing data.


Network Medicine

150pxHumanNet: Human gene networks for disease research

150px TRRUST: Curated TF-target interaction networks in human and mouse

150px COEXPEDIA: Exploring biomedical hypotheses via co-expressions associated with medical subject headings (MeSH)

150px NGSEA: Network-augmented gene set enrichment analysis tool

150px MUFFINN: Cancer gene discovery via network analysis of somatic mutation data

150px GWAB: A web server for network-based boosting of human genome-wide association data

150px MORPHIN: Network-assisted prediction of disease pathways in model organisms

150px RIDDLE: Network-assisted Gene Set Analysis (human only)


Functional Gene Networks

Animals

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Mus musculus Danio rerio Drosophila melanogaster Caenorhabditis elegans

Plants

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Arabidopsis thaliana Zea mays Oryza sativa Triticum aestivum Hordeum vulgare Glycine max Solanum lycopersicum

Fungi

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Saccharomyces cerevisiae Cryptococcus neoformans

Bacteria

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Pseudomonas aeruginosa (human pathogen) Methicillin-resistant Staphylococcus aureus (human pathogen) Klebsiella pneumoniae (human pathogen) Escherichia coli (popular lab/factory bacterial species) Xanthomonas oryzae pv. oryzae (rice pathogen)


Build your own Functional gene networks

150px BiomeNet: A database for construction and analysis of functional interaction networks for any species with a sequenced genome


Network-augmented GWAS Analysis for Arabidopsis

150px araGWAB: genome-wide association boosting for Arabidopsis thaliana


Domain-based PPI networks by Weighted Mutual Information (WMI)

Project Page


Domain2Pathway by Pathway Specificity (PS)

Project Page